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Information Journal Paper

Title

Unexplained High Activity of Aspartate Aminotransferase in an Asymptomatic Pediatric Patient

Pages

  5805-5808

Abstract

 Elevated enzyme activities in plasma may at times be attributed to the presence of Macro-Enzymes. The Macro-Enzymes are often serum enzymes in complex with immunoglobulins, resulting in a greater molecular mass that cannot be filtered by renal glomeruli and are, hence, retained in the plasma. The Aspartate aminotransferase (AST) can exist as a macro-enzyme, although it has been rarely reported. We describe a pediatric patient with persistently elevated serum AST activity, due to macro-enzyme formation between AST and an immunoglobulin. This is to highlight the importance of early diagnosis of macro-AST in an otherwise asymptomatic pediatric patient with isolated AST-elevation and to avoid unnecessary costly testing.

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    APA: Copy

    Maan, Wajiha, Warsi, QurratulAnn, Rashed, Avideh, & KARJOO, MANOOCHEHR. (2017). Unexplained High Activity of Aspartate Aminotransferase in an Asymptomatic Pediatric Patient. INTERNATIONAL JOURNAL OF PEDIATRICS, 5(10 (46)), 5805-5808. SID. https://sid.ir/paper/337792/en

    Vancouver: Copy

    Maan Wajiha, Warsi QurratulAnn, Rashed Avideh, KARJOO MANOOCHEHR. Unexplained High Activity of Aspartate Aminotransferase in an Asymptomatic Pediatric Patient. INTERNATIONAL JOURNAL OF PEDIATRICS[Internet]. 2017;5(10 (46)):5805-5808. Available from: https://sid.ir/paper/337792/en

    IEEE: Copy

    Wajiha Maan, QurratulAnn Warsi, Avideh Rashed, and MANOOCHEHR KARJOO, “Unexplained High Activity of Aspartate Aminotransferase in an Asymptomatic Pediatric Patient,” INTERNATIONAL JOURNAL OF PEDIATRICS, vol. 5, no. 10 (46), pp. 5805–5808, 2017, [Online]. Available: https://sid.ir/paper/337792/en

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