Endocrine Disorders in Beta-thalassemia Major Patients

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CHAHKANDI TAYYEBEH; Norouziasl Samaneh; FARZAD MARJAN; GHANAD FATEMEH

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Journal Paper

Paper Information

Journal: Journal of Pediatric Perspectives Year:2017 | Volume:5 | Issue:8 (44) Page(s): 5531-5538

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Information Journal Paper

Title

Endocrine Disorders in Beta-thalassemia Major Patients

Author(s)

CHAHKANDI TAYYEBEH | Norouziasl Samaneh | FARZAD MARJAN | GHANAD FATEMEH | Issue Writer Certificate

Keywords

Children

Beta-thalassemia Major

Diabetes Mellitus

Endocrine Disorders

Abstract

Background Thalassemia is the most common hereditary disorder worldwide. The patient's’ survival is dependent on lifetime blood transfusion which leads to iron overload and its toxicity on various organs including endocrine glands. The study aimed to investigate Endocrine Disorders in patients with Betathalassemia major in the Southern Khorasan province, Iran. Materials and Methods In this descriptive cross sectional study of the 42 patients with Beta-thalassemia Major blood samples were taken in the fasting to check laboratory tests such as fasting blood sugar, calcium, phosphorous, thyroid stimulating hormone (TSH), thyroxine (T4), luteinizing hormone (LH), follicle stimulating hormone (FSH), parathyroid hormone (PTH), Ferritin. Data analyzed using SPSS version 16. 0 software. Results Results showed that 85. 7% of patients had Endocrine Disorders. The most common endocrine abnormalities were hypogonadism (71. 4%), hypoparathyroidism (21. 4%), diabetes (14. 3%), and hypothyroidism (7. 2%), respectively. Conclusion Our results concluded that endocrine evaluation must be carried out regularly in patients with betathalassemia major. Patients who have abnormal endocrine laboratory results should be reevaluated for compliance with chelation therapy and the transfusion program.

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APA: Copy

CHAHKANDI, TAYYEBEH, Norouziasl, Samaneh, FARZAD, MARJAN, & GHANAD, FATEMEH. (2017). Endocrine Disorders in Beta-thalassemia Major Patients. INTERNATIONAL JOURNAL OF PEDIATRICS, 5(8 (44)), 5531-5538. SID. https://sid.ir/paper/337836/en

Vancouver: Copy

CHAHKANDI TAYYEBEH, Norouziasl Samaneh, FARZAD MARJAN, GHANAD FATEMEH. Endocrine Disorders in Beta-thalassemia Major Patients. INTERNATIONAL JOURNAL OF PEDIATRICS[Internet]. 2017;5(8 (44)):5531-5538. Available from: https://sid.ir/paper/337836/en

IEEE: Copy

TAYYEBEH CHAHKANDI, Samaneh Norouziasl, MARJAN FARZAD, and FATEMEH GHANAD, “Endocrine Disorders in Beta-thalassemia Major Patients,” INTERNATIONAL JOURNAL OF PEDIATRICS, vol. 5, no. 8 (44), pp. 5531–5538, 2017, [Online]. Available: https://sid.ir/paper/337836/en

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