THE COMPARISON OF ORAL AND IM DEXAMETHASONE EFFICACY IN CROUP TREATMENT

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SOLEIMANI GHOLAMREZA; DARYADEL ALIREZA; ANSARI MOGHADAM ALIREZA; SHARIF MOHAMMAD REZA

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Journal Paper

Paper Information

Journal: Journal of Comprehensive Pediatrics Year:2013 | Volume:3 | Issue:5 Page(s): 175-178

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Title

THE COMPARISON OF ORAL AND IM DEXAMETHASONE EFFICACY IN CROUP TREATMENT

Author(s)

SOLEIMANI GHOLAMREZA | DARYADEL ALIREZA | ANSARI MOGHADAM ALIREZA | SHARIF MOHAMMAD REZA | Issue Writer Certificate

Keywords

CROUP

CORTICOSTEROID

DEXAMETHASONE

Abstract

Background: CROUP, or acute laryngotracheobronchitis, is the most common cause of upper airway obstruction in children. Objectives: In this study, the efficacies of intramuscular and oral DEXAMETHASONE administration are compared for treatment of CROUP.Patients and Methods: This is a single-blind randomized trial involving 68 children divided into two groups, the first group received 0.6 mg/kg intramuscular DEXAMETHASONE and the second group received 0.6 mg/kg oral DEXAMETHASONE. The clinical score, respiratory rate, heart rate, O2 saturation and clinical response were assessed before and then hourly for four hours after treatment.Results: The respiratory rate of two groups was significantly different at the first hour of treatment (P=0.02), but it did not vary between study groups at the second, third, and fourth hour of treatment. There was no statistical difference among clinical score, heart rate, O2 saturation and clinical response in any of the measurement times.Conclusions: Oral and intramuscular administrations have the same effectiveness for treatment of CROUP and oral DEXAMETHASONE was proposed because this is a non-invasive procedure.

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APA: Copy

SOLEIMANI, GHOLAMREZA, DARYADEL, ALIREZA, ANSARI MOGHADAM, ALIREZA, & SHARIF, MOHAMMAD REZA. (2013). THE COMPARISON OF ORAL AND IM DEXAMETHASONE EFFICACY IN CROUP TREATMENT. JOURNAL OF COMPREHENSIVE PEDIATRICS, 3(5), 175-178. SID. https://sid.ir/paper/339418/en

Vancouver: Copy

SOLEIMANI GHOLAMREZA, DARYADEL ALIREZA, ANSARI MOGHADAM ALIREZA, SHARIF MOHAMMAD REZA. THE COMPARISON OF ORAL AND IM DEXAMETHASONE EFFICACY IN CROUP TREATMENT. JOURNAL OF COMPREHENSIVE PEDIATRICS[Internet]. 2013;3(5):175-178. Available from: https://sid.ir/paper/339418/en

IEEE: Copy

GHOLAMREZA SOLEIMANI, ALIREZA DARYADEL, ALIREZA ANSARI MOGHADAM, and MOHAMMAD REZA SHARIF, “THE COMPARISON OF ORAL AND IM DEXAMETHASONE EFFICACY IN CROUP TREATMENT,” JOURNAL OF COMPREHENSIVE PEDIATRICS, vol. 3, no. 5, pp. 175–178, 2013, [Online]. Available: https://sid.ir/paper/339418/en

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