THE EFFECT OF CYTOMEGALOVIRUS INFECTION ON ACUTE REJECTION IN KIDNEY TRANSPLANTED PATIENTS

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HASANZAMANI BOSHRA; HAMI MARYAM; ZOLFAGHARI VAJIHE; TORKAMANI MAHTAB; GHORBAN SABAGH MAHIN; AHMADI SIMAB SAIIDEH

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Journal: JOURNAL OF RENAL INJURY PREVENTION Year:2016 | Volume:5 | Issue:2 Page(s): 85-88

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Title

THE EFFECT OF CYTOMEGALOVIRUS INFECTION ON ACUTE REJECTION IN KIDNEY TRANSPLANTED PATIENTS

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Keywords

CYTOMEGALOVIRUS

ACUTE REJECTION

KIDNEY TRANSPLANTATION

Abstract

Introduction: It is known that CYTOMEGALOVIRUS (CMV) infection is a common problem among kidney transplant patients. This infection can be increased morbidity and decreased graft survival. This problem has been associated with ACUTE REJECTION too.Patients and Methods: One hundred and thirty renal transplant patients were included in a prospective, case-control study. The renal transplant patients were divided into two groups; patients group with CMV infection and control group without CMV infection. Serum CMV-IgG in all patients was positive (donor and recipients). None of patients had received anti-thymocyte-globulin and thymoglobulin. CMV infection was diagnosed by quantitative CMV-PCR (polymerase chain reaction) test (more than 500 copies/μg). Rejection episode was defined by kidney isotope scan or biopsy.Results: In the group of 66 CMV infection patients (41 male [62.1%] and 25 female [37.9%]) the incidence of graft rejection was 36%, however in the group of 64 control patients the incidence of graft rejection was 9.4% (P<0.005).Conclusion: CMV infection is important predisposing factor for acute allograft rejection after KIDNEY TRANSPLANTATION. The results of this study suggests that the control of CMV infection could decrease episodes of acute kidney rejection.

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APA: Copy

HASANZAMANI, BOSHRA, HAMI, MARYAM, ZOLFAGHARI, VAJIHE, TORKAMANI, MAHTAB, GHORBAN SABAGH, MAHIN, & AHMADI SIMAB, SAIIDEH. (2016). THE EFFECT OF CYTOMEGALOVIRUS INFECTION ON ACUTE REJECTION IN KIDNEY TRANSPLANTED PATIENTS. JOURNAL OF RENAL INJURY PREVENTION, 5(2), 85-88. SID. https://sid.ir/paper/341028/en

Vancouver: Copy

HASANZAMANI BOSHRA, HAMI MARYAM, ZOLFAGHARI VAJIHE, TORKAMANI MAHTAB, GHORBAN SABAGH MAHIN, AHMADI SIMAB SAIIDEH. THE EFFECT OF CYTOMEGALOVIRUS INFECTION ON ACUTE REJECTION IN KIDNEY TRANSPLANTED PATIENTS. JOURNAL OF RENAL INJURY PREVENTION[Internet]. 2016;5(2):85-88. Available from: https://sid.ir/paper/341028/en

IEEE: Copy

BOSHRA HASANZAMANI, MARYAM HAMI, VAJIHE ZOLFAGHARI, MAHTAB TORKAMANI, MAHIN GHORBAN SABAGH, and SAIIDEH AHMADI SIMAB, “THE EFFECT OF CYTOMEGALOVIRUS INFECTION ON ACUTE REJECTION IN KIDNEY TRANSPLANTED PATIENTS,” JOURNAL OF RENAL INJURY PREVENTION, vol. 5, no. 2, pp. 85–88, 2016, [Online]. Available: https://sid.ir/paper/341028/en

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