COMPARISON OF RADIOTHERAPY WITH CHEMORADIOTHERAPY FOR TREATMENT OF SQUAMOUS CELL CARCINOMA OF HEAD AND NECK: A RANDOMIZED CLINICAL TRIAL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOSALAEI A.; LARIZADEH M.H.; SALBIAN M.J.; OMIDVARI S.; MOHAMMADIANPANAH M.; AHMADI KOHANALI JAFAR

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN SOUTH MEDICAL JOURNAL (ISMJ) Year:2002 | Volume:5 | Issue:1 Page(s): 36-40

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

6,774

Download:

Cites:

Information Journal Paper

Title

COMPARISON OF RADIOTHERAPY WITH CHEMORADIOTHERAPY FOR TREATMENT OF SQUAMOUS CELL CARCINOMA OF HEAD AND NECK: A RANDOMIZED CLINICAL TRIAL

Author(s)

Keywords

SQUAMOUS CELL CARCINOMAQ4

HEAD AND NECK TUMORQ2

RADIOTHERAPYQ3

CHEMOTHERAPYQ3

Abstract

Introduction: Squamaus cell carcinoma is the most common tumor of head and neck. According to clinical stage of disease, RADIOTHERAPY and/or surgery is (are) used far treatment of these tumors. Although improvement of treatment results has been reported with chemoradiotherapy, still some controversy exists about the benefit of adding CHEMOTHERAPY. This study-compares chemoradiotherapy vs RADIOTHERAPY alone. Materials and methods: One hundred and fifty patients with SQUAMOUS CELL CARCINOMA of head and neck were categorized into two groups randomly. The first group was designed to receive conventional fractionation radiation therapy (75 patients), ranging from 50 to 70 Gy (5 fractions per week and 2 Gy per fraction) and the other group was planned to get combined chemoradiotherapy (75 patients). CHEMOTHERAPY regimen consisted of cisplatin (100mg/m2) and 5-flluorouracil (750mg/m2), given every 3 weeks concurrent or after RADIOTHERAPY. Results: Initial response was seen in 69.4% following RADIOTHERAPY and 85.7% after chemoradiation (p=0.031). Recurrence (locoregional or distant) was seen in 46.7% and 26.2% of patients in RADIOTHERAPY and CHEMOTHERAPY group, respectively. Mean time for recurrence after treatment was 8.58 and 7.17 months in 2 groups, respectively.Conclusion: Addition of CHEMOTHERAPY to RADIOTHERAPY causes decrease in recurrence and increase in initial response rate in squamous cell cancers of head and neck.

Cites

No record.

References

No record.

Cite

APA: Copy

MOSALAEI, A., LARIZADEH, M.H., SALBIAN, M.J., OMIDVARI, S., MOHAMMADIANPANAH, M., & AHMADI KOHANALI, JAFAR. (2002). COMPARISON OF RADIOTHERAPY WITH CHEMORADIOTHERAPY FOR TREATMENT OF SQUAMOUS CELL CARCINOMA OF HEAD AND NECK: A RANDOMIZED CLINICAL TRIAL. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 5(1), 36-40. SID. https://sid.ir/paper/34125/en

Vancouver: Copy

MOSALAEI A., LARIZADEH M.H., SALBIAN M.J., OMIDVARI S., MOHAMMADIANPANAH M., AHMADI KOHANALI JAFAR. COMPARISON OF RADIOTHERAPY WITH CHEMORADIOTHERAPY FOR TREATMENT OF SQUAMOUS CELL CARCINOMA OF HEAD AND NECK: A RANDOMIZED CLINICAL TRIAL. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2002;5(1):36-40. Available from: https://sid.ir/paper/34125/en

IEEE: Copy

A. MOSALAEI, M.H. LARIZADEH, M.J. SALBIAN, S. OMIDVARI, M. MOHAMMADIANPANAH, and JAFAR AHMADI KOHANALI, “COMPARISON OF RADIOTHERAPY WITH CHEMORADIOTHERAPY FOR TREATMENT OF SQUAMOUS CELL CARCINOMA OF HEAD AND NECK: A RANDOMIZED CLINICAL TRIAL,” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 5, no. 1, pp. 36–40, 2002, [Online]. Available: https://sid.ir/paper/34125/en

Related Journal Papers