STUDY OF THE ROLE OF COMBINED RADIOTHERAPY & CHEMOTHERAPY IN TREATMENT OF SQUAMOUS CELL TUMORS OF HEAD AND NECK

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOSALAEI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2003 | Volume:8 | Issue:4 Page(s): 85-88

Download Full-Text

Persian Verion

View:

1,699

Download:

Cites:

Information Journal Paper

Title

STUDY OF THE ROLE OF COMBINED RADIOTHERAPY & CHEMOTHERAPY IN TREATMENT OF SQUAMOUS CELL TUMORS OF HEAD AND NECK

Author(s)

MOSALAEI A. | | | Issue Writer Certificate

Keywords

SQUMOUS CELL CARCINOMAQ4

HEAD AND NECK TUMORQ4

RADIOTHERAPYQ4

CHEMOTHERAPYQ4

Abstract

Introduction: Squamous cell carcinoma is the most common tumor of head and neck. According to clinical stage of disease, RADIOTHERAPY and/or surgery is (are) used for treatment of these tumos. Although improvement of treatment results has been reported with chemoradiotherapy , still some controversy exists about the benefit of adding CHEMOTHERAPY. This study compares chemoradiotherapy vs. RADIOTHERAPY alone.Materials and methods: One hundred and fifty five patients with squamous cell carcinoma of head and neck were categorized into two groups randomly. The first group was designed to receive conventional fractionation radiation therapy (90 Patients) , ranging from 50 to 70 Gy (5fractions per week and 2 Gy per fraction) and the other group was planned to get combined chemoradiotherapy (65 patients) .Chemotherapy regimen consisted of Cisplatin (100mg/m2) and 5,f-u (750 mg/m2), given 3 weeks concurrent or after RADIOTHERAPY. For statistical analysis Fischer exact test and independent T-test were used.Results: Initial response was seen in 69.4% following RADIOTHERAPY and 85.7% after chemoradiation (p=0.031). Recurrence (Locoregional or distant) was seen in 46.7% and 26.2% of patients in RADIOTHERAPY and CHEMOTHERAPY group, respectively. Mean time for recurrence after treatment was 8.58 and 7.17 months in 2 groups, respectively.Conclusion: Addition of CHEMOTHERAPY to RADIOTHERAPY causes decrease in recurrence and increase in initial response rate in squamous cell cancers of head and neck.

Cites

No record.

References

No record.

Cite

APA: Copy

MOSALAEI, A.. (2003). STUDY OF THE ROLE OF COMBINED RADIOTHERAPY & CHEMOTHERAPY IN TREATMENT OF SQUAMOUS CELL TUMORS OF HEAD AND NECK. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 8(4), 85-88. SID. https://sid.ir/paper/26620/en

Vancouver: Copy

MOSALAEI A.. STUDY OF THE ROLE OF COMBINED RADIOTHERAPY & CHEMOTHERAPY IN TREATMENT OF SQUAMOUS CELL TUMORS OF HEAD AND NECK. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2003;8(4):85-88. Available from: https://sid.ir/paper/26620/en

IEEE: Copy

A. MOSALAEI, “STUDY OF THE ROLE OF COMBINED RADIOTHERAPY & CHEMOTHERAPY IN TREATMENT OF SQUAMOUS CELL TUMORS OF HEAD AND NECK,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 8, no. 4, pp. 85–88, 2003, [Online]. Available: https://sid.ir/paper/26620/en

Related Journal Papers