SURVIVAL RATE AND ASSOCIATED FACTORS OF CHILDHOOD LEUKEMIA IN IRAN: A SYSTEMATIC REVIEW AND META ANALYSIS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

VEISANI YOUSEF; DELPISHEH ALI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Pediatrics Review Year:2017 | Volume:5 | Issue:2 Page(s): 0-0

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

SURVIVAL RATE AND ASSOCIATED FACTORS OF CHILDHOOD LEUKEMIA IN IRAN: A SYSTEMATIC REVIEW AND META ANALYSIS

Author(s)

VEISANI YOUSEF | DELPISHEH ALI | Issue Writer Certificate

Keywords

LEUKEMIA

ACUTE MYELOID LEUKEMIA

ACUTE LYMPHOCYTIC LEUKEMIA

SURVIVAL RATE

META-ANALYSIS

Abstract

Context: Resent reviews have shown that about 18% of all child cancers are LEUKEMIA. Track of the SURVIVAL RATE can help researchers improve quality of life of patients through improving screening or discovery of better treatments.Objectives: This review aimed at estimating the 5-year SURVIVAL RATEs and associated factors of childhood LEUKEMIA in Iran.Data Sources: We carried out a systematic review through search of relevant studies published in English (PubMed, Scopus, Google scholar, and ISI) and Persian databases (Magiran, Medlib, SID, and Iran Medex).Study Selection: The study included all epidemiologic studies that estimated SURVIVAL RATE in children with LEUKEMIA in Iran during years 2002 to 2015, and a standardized manner was used for extraction of information.Data Extraction: The entire text or summary of all searched articles was extracted and then, related articles were selected, and irrelevant ones were excluded. Fixed and random effects models were calculated by the STATA using standard META-ANALYSIS methods.Heterogeneity was assessed by I2 statistics.Results: The overall 5-year SURVIVAL RATE in patients with childhood LEUKEMIA in Iran was 0.65 (95% CI, 0.62 to 0.67, 10 studies), in the acute lymphoblastic LEUKEMIA (ALL) subtype was 71.0% (95% CI: 68.0 to 74.0), and in the acute myeloid LEUKEMIA (AML) subtype was 46.0%. Results of the meta analysis showed significant poor survival with relapse (heart rate (HR) 1.59, 95% confidence interval (CI) 1.27 to 1.98) and white blood count (WBC) counts 50, 000 (HR 2.92, 95% CI 1.23 to 4.60).Conclusions: The results showed that 5-year SURVIVAL RATEs in patients withAMLwere lower than patients with ALL. The results of this meta analysis strongly support the need for future research, action, and guidance for clinicians to improve health-related quality of life and outcomes for children with LEUKEMIA.

Cites