99MTC MAA SPECT/CT QUANTIFICATION OF LUNG MASS AND LIVER-TO-LUNG SHUNTING PRIOR TO 90Y RADIOEMBOLIZATION

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MAGSOMBOL BUTCH MAULION

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Journal Paper

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Journal: Asia Oceania Journal of Nuclear Medicine & Biology Year:2014 | Volume:2 | Issue:SUPPLEMENT 1 Page(s): 35-35

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Title

99MTC MAA SPECT/CT QUANTIFICATION OF LUNG MASS AND LIVER-TO-LUNG SHUNTING PRIOR TO 90Y RADIOEMBOLIZATION

Author(s)

MAGSOMBOL BUTCH MAULION

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Abstract

Background: Applying the MIRD assumption of a 1000g lung mass it is estimated that 3.0 GBq of 90Y SIR-spheres in a patient with 20% mean liver-to-lung shunt ratio will receive a mean lung dose of approximately 30 Gy. The objective was to assess the variability in the patient-specific lung mass of our patients going for 90Y radioembolization. To assess the differences between the liver-to-lung ratios (LLR) estimated by planar scintigraphy and SPECT/CT.Material and Methods: Seventy five patients underwent hepatic angiogram and 99mTc MAA injection for assessment of hepatic vasculature and dosimetry. Planar and SPECT/CT images were obtained to derive the LLR. Specific lung masses were derived from CT morphometry.Results: Planar scintigraphy slightly overestimated the SPECT/CT LLR by an average of 2.09%. The mean lung mass in our patient population is 690g (726.3g for males, 564.9g for females) therefore the MIRD lung mass overestimates the mean lung mass by 310g.Conclusion: Lung morphometry derived from SPECT/CT data achieves patient-specific dosimetry for safer radioembolization.

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APA: Copy

MAGSOMBOL, BUTCH MAULION. (2014). ^99MTC MAA SPECT/CT QUANTIFICATION OF LUNG MASS AND LIVER-TO-LUNG SHUNTING PRIOR TO ⁹⁰Y RADIOEMBOLIZATION. ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY, 2(SUPPLEMENT 1), 35-35. SID. https://sid.ir/paper/341978/en

Vancouver: Copy

MAGSOMBOL BUTCH MAULION. ^99MTC MAA SPECT/CT QUANTIFICATION OF LUNG MASS AND LIVER-TO-LUNG SHUNTING PRIOR TO ⁹⁰Y RADIOEMBOLIZATION. ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY[Internet]. 2014;2(SUPPLEMENT 1):35-35. Available from: https://sid.ir/paper/341978/en

IEEE: Copy

BUTCH MAULION MAGSOMBOL, “^99MTC MAA SPECT/CT QUANTIFICATION OF LUNG MASS AND LIVER-TO-LUNG SHUNTING PRIOR TO ⁹⁰Y RADIOEMBOLIZATION,” ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY, vol. 2, no. SUPPLEMENT 1, pp. 35–35, 2014, [Online]. Available: https://sid.ir/paper/341978/en

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