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Information Journal Paper

Title

ETHNOPHARMACOLOGY, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF DITTRICHIA GRAVEOLENS (L.) W. GREUTER. WHICH HAS BEEN USED AS REMEDIES ANTIRHEUMATIC, ANTI-INFLAMMATION AND ANTIINFECTION AGAINST LEISHMANIASIS IN THE TRADITIONAL MEDICINE OF GORGAN, IRAN

Pages

  125-129

Keywords

DITTRICHIA GRAVEOLENS (L.) W. GREUTER 

Abstract

 Objective: This study was survey to investigate of ETHNOPHARMACOLOGY, ANTIBACTERIAL and ANTIOXIDANT capacity of Dittrichia graveolens (L.) W. Greuter extract in in vitro from waste ground region of GORGAN, Iran, which has been used in traditional as a strong anti-inflammation, antirheumatism, antitumor, antipathogene, and antiinfection.Materials and Methods: Ethnopharmacological data were obtained among well-known indigenous herbal practitioner (70 ages) in GORGAN, Iran. Aerial parts of plant in blooming were collected from GORGAN waste ground (80 m) in October 2013. Methanol and acetone extracts were obtained by maceration, ANTIOXIDANT activity were evaluated spectrophotometrically by 1,1-diphenyl-2-picryl hydrazyl (DPPH), total ANTIOXIDANT capacity and reducing power to compare of butylated hydroxytoluene and butylated hydroxyanisole ANTIOXIDANT standard and ANTIBACTERIAL activity were determined by disc diffusion and minimal inhibitory concentrations (MICs) method against tree Gram-positive and negative pathogenic bacteria.Results: D. graveolens (L.) W. Greuteris is usually wild grow in Golestan Province and has been used in traditional medicine as a strong anti-inflammation, antirheumatism, antitumor, antipathogene and antiinfection specially in treat of leishmaniosis metanolic extract of plant has strong ANTIOXIDANT activity against free radical scavenging specially in DPPH methode than aceton extract with IC50 (6.2±0.13 mg/ml) and Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis and Bacillus cereus with inhibition zone 35, 30, 26, 21 mm were the most sensitive bacteria, with MIC ranging from 12.6 to 112 mg/ml, respectively. Escherichia coli and Salmonella typhimurium have moderate sensitivity and other bacteria were resistant to the plant extract.Conclusion: Results demonstrate that the methanolic extract of D. graveolens can become good potential ANTIOXIDANT and ANTIBACTERIAL activity for controlling certain Gram-positive and negative bacteria, which produces many infectious diseases.

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    APA: Copy

    MAZANDARANI, MASOUMEH, GHAFOURIAN, MOHAMMAD, & KHORMALI, AYESHEH. (2014). ETHNOPHARMACOLOGY, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF DITTRICHIA GRAVEOLENS (L.) W. GREUTER. WHICH HAS BEEN USED AS REMEDIES ANTIRHEUMATIC, ANTI-INFLAMMATION AND ANTIINFECTION AGAINST LEISHMANIASIS IN THE TRADITIONAL MEDICINE OF GORGAN, IRAN. CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES, 1(4), 125-129. SID. https://sid.ir/paper/344923/en

    Vancouver: Copy

    MAZANDARANI MASOUMEH, GHAFOURIAN MOHAMMAD, KHORMALI AYESHEH. ETHNOPHARMACOLOGY, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF DITTRICHIA GRAVEOLENS (L.) W. GREUTER. WHICH HAS BEEN USED AS REMEDIES ANTIRHEUMATIC, ANTI-INFLAMMATION AND ANTIINFECTION AGAINST LEISHMANIASIS IN THE TRADITIONAL MEDICINE OF GORGAN, IRAN. CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES[Internet]. 2014;1(4):125-129. Available from: https://sid.ir/paper/344923/en

    IEEE: Copy

    MASOUMEH MAZANDARANI, MOHAMMAD GHAFOURIAN, and AYESHEH KHORMALI, “ETHNOPHARMACOLOGY, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF DITTRICHIA GRAVEOLENS (L.) W. GREUTER. WHICH HAS BEEN USED AS REMEDIES ANTIRHEUMATIC, ANTI-INFLAMMATION AND ANTIINFECTION AGAINST LEISHMANIASIS IN THE TRADITIONAL MEDICINE OF GORGAN, IRAN,” CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES, vol. 1, no. 4, pp. 125–129, 2014, [Online]. Available: https://sid.ir/paper/344923/en

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