مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

PROTECTIVE EFFECT OF OCIMUM BASILICUM ON BRAIN CELLS EXPOSED TO OXIDATIVE DAMAGE BY ELECTROMAGNETIC FIELD IN RAT: ULTRASTRUCTURAL STUDY BY TRANSMISSION ELECTRON MICROSCOPY

Pages

  1-7

Abstract

 Objective: Basil herb (Ocimum basilicum) has long been used in human nutrition. Nowadays antioxidant role of this herb is known more. The aim of this study was to study the anti-oxidative property of sweet basil to protect central nervous system against OXIDATIVE DAMAGEs of electromagnetic field (EMF) and its affective sequences.Materials and Methods: Forty Albino male Wistar rats were randomly allocated to four groups, 10 rats per each. Group 1 received normal diet (control group), group 2 was exposed to 50 Hz EMF for 8 weeks (EMF group). Group 3 was exposed to 50 Hz EMF and fed with basil extract (0.5 g/kg body weight) for 8 weeks (treatment group) and group 4 was fed with basil extract (0.5 g/kg body weight) for 8 weeks and named as herbal group. At the end of eighth week 5 mL blood was taken from all rats for biochemical analysis and for ultra structural study of BRAIN neuron samples was taken.Results: The results showed level of superoxide dismutase (SOD), glutathione (GSH) peroxidase and catalase activity (CAT) were significantly increased in herbal and treatment groups as compared to EMF group (P<0.05). Level of malondialdehyde (MDA) was significantly decreased in treatment group as compare to EMF group (P<0.05). Ultra structural evaluation of EMF group showed BRAIN nucleus has a lot of heterochromatic changes and mitochondria have been ovulated and have swelling figure this changes were less in treatment group.Conclusion: Antioxidant capacity of basil extract can cause to decrease oxidative effects of EMF on BRAIN tissue and in rats.

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    APA: Copy

    KHAKI, ARASH. (2016). PROTECTIVE EFFECT OF OCIMUM BASILICUM ON BRAIN CELLS EXPOSED TO OXIDATIVE DAMAGE BY ELECTROMAGNETIC FIELD IN RAT: ULTRASTRUCTURAL STUDY BY TRANSMISSION ELECTRON MICROSCOPY. CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES, 3(1), 1-7. SID. https://sid.ir/paper/344931/en

    Vancouver: Copy

    KHAKI ARASH. PROTECTIVE EFFECT OF OCIMUM BASILICUM ON BRAIN CELLS EXPOSED TO OXIDATIVE DAMAGE BY ELECTROMAGNETIC FIELD IN RAT: ULTRASTRUCTURAL STUDY BY TRANSMISSION ELECTRON MICROSCOPY. CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES[Internet]. 2016;3(1):1-7. Available from: https://sid.ir/paper/344931/en

    IEEE: Copy

    ARASH KHAKI, “PROTECTIVE EFFECT OF OCIMUM BASILICUM ON BRAIN CELLS EXPOSED TO OXIDATIVE DAMAGE BY ELECTROMAGNETIC FIELD IN RAT: ULTRASTRUCTURAL STUDY BY TRANSMISSION ELECTRON MICROSCOPY,” CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES, vol. 3, no. 1, pp. 1–7, 2016, [Online]. Available: https://sid.ir/paper/344931/en

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