SERUM LEVELS OF INTERLEUKIN-27 AND INTERLEUKIN-33 IN PATIENTS WITH DERMATOMYOSITIS AND POLYMYOSITIS COMPARED TO HEALTHY CONTROL SUBJECTS

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SHAHRYARI GELLARE; SHAHRAKI ALI; ZAKERI ZAHRA

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Journal: Gene, Cell and Tissue Year:2015 | Volume:2 | Issue:4 Page(s): 0-0

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Information Journal Paper

Title

SERUM LEVELS OF INTERLEUKIN-27 AND INTERLEUKIN-33 IN PATIENTS WITH DERMATOMYOSITIS AND POLYMYOSITIS COMPARED TO HEALTHY CONTROL SUBJECTS

Author(s)

SHAHRYARI GELLARE | SHAHRAKI ALI | ZAKERI ZAHRA | Issue Writer Certificate

Keywords

DERMATOMYOSITIS

POLYMYOSITIS

INTERLEUKIN-27

INTERLEUKIN-33

Abstract

Background: In some autoimmune diseases such as rheumatoid arthritis (RA), INTERLEUKIN-27 (IL-27) and IL-33 levels are increased. These observations suggest that IL-27 and IL-33 may have a role in the pathogenesis of POLYMYOSITIS/DERMATOMYOSITIS (PM/DM).Objectives: The aim of this study was to assess IL-27 and IL-33 levels in PM/DM patients compared to healthy control subjects.Patients and Methods: Twenty patients with DM and nine patients with PM were recruited in this study. Twenty-nine healthy controls whose age and gender were matched with the patients were also recruited. Serum IL-27 and IL-33 was measured by the Enzyme-Linked Immunosorbent Assay (ELISA).Results: The serum levels of IL-27 in patients with DM and PM were higher than those of healthy controls. There were no significant differences in serum levels of IL-33 in patients with DM and PM compared to the healthy control group.Conclusions: These data indicate that IL-27 might be selectively involved in the pathogenesis of DM and PM. However, IL-33 does not appear to be influenced.

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APA: Copy

SHAHRYARI, GELLARE, SHAHRAKI, ALI, & ZAKERI, ZAHRA. (2015). SERUM LEVELS OF INTERLEUKIN-27 AND INTERLEUKIN-33 IN PATIENTS WITH DERMATOMYOSITIS AND POLYMYOSITIS COMPARED TO HEALTHY CONTROL SUBJECTS. GENE, CELL AND TISSUE, 2(4), 0-0. SID. https://sid.ir/paper/345084/en

Vancouver: Copy

SHAHRYARI GELLARE, SHAHRAKI ALI, ZAKERI ZAHRA. SERUM LEVELS OF INTERLEUKIN-27 AND INTERLEUKIN-33 IN PATIENTS WITH DERMATOMYOSITIS AND POLYMYOSITIS COMPARED TO HEALTHY CONTROL SUBJECTS. GENE, CELL AND TISSUE[Internet]. 2015;2(4):0-0. Available from: https://sid.ir/paper/345084/en

IEEE: Copy

GELLARE SHAHRYARI, ALI SHAHRAKI, and ZAHRA ZAKERI, “SERUM LEVELS OF INTERLEUKIN-27 AND INTERLEUKIN-33 IN PATIENTS WITH DERMATOMYOSITIS AND POLYMYOSITIS COMPARED TO HEALTHY CONTROL SUBJECTS,” GENE, CELL AND TISSUE, vol. 2, no. 4, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/345084/en

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