HISTOPATHOLOGICAL FINDINGS IN CHOLESTERYL ESTER STORAGE DISEASE: A REPORT OF THREE CASES

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SHAHRAMIAN IRAJ; AZIMI KHATIBI ESMAEIL; MAHJOOB FATEMEH; SARGAZI ALIYEH; DELARAMNASAB MOJTABA; BAZI ALI

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Journal: Gene, Cell and Tissue Year:2017 | Volume:4 | Issue:3 Page(s): 0-0

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Title

HISTOPATHOLOGICAL FINDINGS IN CHOLESTERYL ESTER STORAGE DISEASE: A REPORT OF THREE CASES

Author(s)

Keywords

CHOLESTERYL ESTER STORAGE DISEASE

LYSOSOMAL STORAGE DISEASES

LIPIDOSES

HEPATOLOGY

HISTOPATHOLOGY

TRIGLYCERIDE

Abstract

CHOLESTERYL ESTER STORAGE DISEASE (CESD) is a disorder in which cholesteryl esters (CE) and TRIGLYCERIDEs (TG) are preserved particularly in hepatocytes. The exact clinical manifestation is not known due to a lack of sufficient data. The current study presents 3 new cases of CESD with 2 of them being siblings. All had perturbed serum low-density lipoprotein (LDL), lactate dehydrogenase (LDH), TRIGLYCERIDE, and cholesterol. Hepatosplenomegaly was seen in all the patients. Liver biopsy showed fat storage in hepatocytes.Adrenomegaly or adrenal calcification, portal hypertension, esophageal varices, and hepatic scarring were not observed in any of the patients. Histopathologic features of CESD, including fat storage in hepatocytes, could characterize these patients.

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APA: Copy

SHAHRAMIAN, IRAJ, AZIMI KHATIBI, ESMAEIL, MAHJOOB, FATEMEH, SARGAZI, ALIYEH, DELARAMNASAB, MOJTABA, & BAZI, ALI. (2017). HISTOPATHOLOGICAL FINDINGS IN CHOLESTERYL ESTER STORAGE DISEASE: A REPORT OF THREE CASES. GENE, CELL AND TISSUE, 4(3), 0-0. SID. https://sid.ir/paper/345132/en

Vancouver: Copy

SHAHRAMIAN IRAJ, AZIMI KHATIBI ESMAEIL, MAHJOOB FATEMEH, SARGAZI ALIYEH, DELARAMNASAB MOJTABA, BAZI ALI. HISTOPATHOLOGICAL FINDINGS IN CHOLESTERYL ESTER STORAGE DISEASE: A REPORT OF THREE CASES. GENE, CELL AND TISSUE[Internet]. 2017;4(3):0-0. Available from: https://sid.ir/paper/345132/en

IEEE: Copy

IRAJ SHAHRAMIAN, ESMAEIL AZIMI KHATIBI, FATEMEH MAHJOOB, ALIYEH SARGAZI, MOJTABA DELARAMNASAB, and ALI BAZI, “HISTOPATHOLOGICAL FINDINGS IN CHOLESTERYL ESTER STORAGE DISEASE: A REPORT OF THREE CASES,” GENE, CELL AND TISSUE, vol. 4, no. 3, pp. 0–0, 2017, [Online]. Available: https://sid.ir/paper/345132/en

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