EFFECT OF LEVISTICUM OFFICINALE HYDROALCOHOLIC EXTRACT ON DU-145 AND PC-3 PROSTATE CANCER CELL LINES

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SARGAZI SAMAN; SARAVANI RAMIN; Galavi Hamid Reza; MOLLASHAHEE KOHKAN FATEMEH

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Journal: Gene, Cell and Tissue Year:2017 | Volume:4 | Issue:4 Page(s): 0-0

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Title

EFFECT OF LEVISTICUM OFFICINALE HYDROALCOHOLIC EXTRACT ON DU-145 AND PC-3 PROSTATE CANCER CELL LINES

Author(s)

SARGAZI SAMAN | SARAVANI RAMIN | Galavi Hamid Reza | MOLLASHAHEE KOHKAN FATEMEH | Issue Writer Certificate

Keywords

PROSTATE CANCER

CYTOTOXIC EFFECTS

CELL DEATH

LEVISTICUM OFFICINALE

Abstract

Levisticum officinalecontains a variety of components used for its medicinal properties in traditional medicine. The previous studies showed that it had an anti-cancer effect on cell lines. The current study aims to evaluate the cytotoxic potential of LEVISTICUM OFFICINALE hydroalcoholic extract (LOHE) on DU-145 and PC-3 human advanced PROSTATE CANCER cell lines. The anti-proliferative activity of LOHE was evaluated using the MTT assay. The results of MTT showed that the IC50 of DU-145 and PC-3 were 500mg/mL and 400 mg/mL ofLOHE, respectively, following 24 hours treatment. This study found that the hydroalcoholic extract of LEVISTICUM OFFICINALE had beneficial CELL DEATH inducing effects on both the PC3 and DU145 human prostate carcinoma cell lines in time- and concentrationdependent fashion. Hence, LOHE may have remarkable potential for uses as new natural anticancer agent.

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APA: Copy

SARGAZI, SAMAN, SARAVANI, RAMIN, Galavi, Hamid Reza, & MOLLASHAHEE KOHKAN, FATEMEH. (2017). EFFECT OF LEVISTICUM OFFICINALE HYDROALCOHOLIC EXTRACT ON DU-145 AND PC-3 PROSTATE CANCER CELL LINES. GENE, CELL AND TISSUE, 4(4), 0-0. SID. https://sid.ir/paper/345141/en

Vancouver: Copy

SARGAZI SAMAN, SARAVANI RAMIN, Galavi Hamid Reza, MOLLASHAHEE KOHKAN FATEMEH. EFFECT OF LEVISTICUM OFFICINALE HYDROALCOHOLIC EXTRACT ON DU-145 AND PC-3 PROSTATE CANCER CELL LINES. GENE, CELL AND TISSUE[Internet]. 2017;4(4):0-0. Available from: https://sid.ir/paper/345141/en

IEEE: Copy

SAMAN SARGAZI, RAMIN SARAVANI, Hamid Reza Galavi, and FATEMEH MOLLASHAHEE KOHKAN, “EFFECT OF LEVISTICUM OFFICINALE HYDROALCOHOLIC EXTRACT ON DU-145 AND PC-3 PROSTATE CANCER CELL LINES,” GENE, CELL AND TISSUE, vol. 4, no. 4, pp. 0–0, 2017, [Online]. Available: https://sid.ir/paper/345141/en

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