COMPARISON OF GATED SPECT MYOCARDIAL PERFUSION IMAGING WITH ECHOCARDIOGRAPHY FOR THE MEASUREMENT OF LEFT VENTRICULAR VOLUMES AND EJECTION FRACTION IN PATIENTS WITH SEVERE HEART FAILURE

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SHOJAEIFARD MARYAM; GHAEDIAN TAHEREH; YAGHOOBI NAHID; MALEK HADI; FIROOZABADI HASAN; BITARAFAN RAJABI AHMAD; HAGHJOO MAJID; AMIN AHMAD; AZIZIAN NASRIN; RASTGOU FERIDOON

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Journal: RESEARCH IN CARDIOVASCULAR MEDICINE Year:2016 | Volume:5 | Issue:1 Page(s): 0-0

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Title

COMPARISON OF GATED SPECT MYOCARDIAL PERFUSION IMAGING WITH ECHOCARDIOGRAPHY FOR THE MEASUREMENT OF LEFT VENTRICULAR VOLUMES AND EJECTION FRACTION IN PATIENTS WITH SEVERE HEART FAILURE

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Keywords

LEFT VENTRICULAR

ECHOCARDIOGRAPHY

CARDIAC-GATED SINGLE-PHOTON EMISSION COMPUTER-ASSISTED TOMOGRAPHY

Abstract

Background: Gated single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is known as a feasible tool for the measurement of LEFT VENTRICULAR ejection fraction (EF) and volumes, which are of great importance in the management and follow-up of patients with coronary artery diseases. However, considering the technical shortcomings of SPECT in the presence of perfusion defect, the accuracy of this method in heart failure patients is still controversial.Objectives: The aim of the present study was to compare the results from gated SPECT MPI with those from ECHOCARDIOGRAPHY in heart failure patients to compare echocardiographically-derived LEFT VENTRICULAR dimension and function data to those from gated SPECT MPI in heart failure patients.Patients and Methods: Forty-one patients with severely reduced LEFT VENTRICULAR systolic function (EF£35%) who were referred for gated SPECT MPI were prospectively enrolled. Quantification of EF, end-diastolic volume (EDV), and end-systolic volume (ESV) was performed by using quantitative gated spect (QGS) (QGS, version 0.4, May 2009) and emory cardiac toolbox (ECTb) (ECTb, revision 1.0, copyright 2007) software packages. EF, EDV, and ESV were also measured with two-dimensional ECHOCARDIOGRAPHY within 3 days after MPI.Results: A good correlation was found between echocardiographically-derived EF, EDV, and ESV and the values derived using QGS (r=0.67, r=0.78, and r=0.80 for EF, EDV, and ESV, respectively; P<0.001) and ECTb (r=0.68, 0.79, and r=0.80 for EF, EDV, and ESV, respectively; P<0.001). However, Bland-Altman plots indicated significantly different mean values for EF, 11.4 and 20.9 using QGS and ECTb, respectively, as compared with ECHOCARDIOGRAPHY. ECTb-derived EDV was also significantly higher than the EDV measured with ECHOCARDIOGRAPHY and QGS. The highest correlation between ECHOCARDIOGRAPHY and gated SPECT MPI was found for mean values of ESV different.Conclusions: Gated SPECT MPI has a good correlation with ECHOCARDIOGRAPHY for the measurement of LEFT VENTRICULAR EF, EDV, and ESV in patients with severe heart failure. However, the absolute values of these functional parameters from ECHOCARDIOGRAPHY and gated SPECT MPI measured with different software packages should not be used interchangeably.

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References

LV DYSSYNCHRONY ASSESSED WITH PHASE ANALYSIS ON GATED MYOCARDIAL PERFUSION SPECT CAN PREDICT RESPONSE TO CRT IN PATIENTS WITH END-STAGE HEART FAILURE

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APA: Copy

SHOJAEIFARD, MARYAM, GHAEDIAN, TAHEREH, YAGHOOBI, NAHID, MALEK, HADI, FIROOZABADI, HASAN, BITARAFAN RAJABI, AHMAD, HAGHJOO, MAJID, AMIN, AHMAD, AZIZIAN, NASRIN, & RASTGOU, FERIDOON. (2016). COMPARISON OF GATED SPECT MYOCARDIAL PERFUSION IMAGING WITH ECHOCARDIOGRAPHY FOR THE MEASUREMENT OF LEFT VENTRICULAR VOLUMES AND EJECTION FRACTION IN PATIENTS WITH SEVERE HEART FAILURE. RESEARCH IN CARDIOVASCULAR MEDICINE, 5(1), 0-0. SID. https://sid.ir/paper/346923/en

Vancouver: Copy

SHOJAEIFARD MARYAM, GHAEDIAN TAHEREH, YAGHOOBI NAHID, MALEK HADI, FIROOZABADI HASAN, BITARAFAN RAJABI AHMAD, HAGHJOO MAJID, AMIN AHMAD, AZIZIAN NASRIN, RASTGOU FERIDOON. COMPARISON OF GATED SPECT MYOCARDIAL PERFUSION IMAGING WITH ECHOCARDIOGRAPHY FOR THE MEASUREMENT OF LEFT VENTRICULAR VOLUMES AND EJECTION FRACTION IN PATIENTS WITH SEVERE HEART FAILURE. RESEARCH IN CARDIOVASCULAR MEDICINE[Internet]. 2016;5(1):0-0. Available from: https://sid.ir/paper/346923/en

IEEE: Copy

MARYAM SHOJAEIFARD, TAHEREH GHAEDIAN, NAHID YAGHOOBI, HADI MALEK, HASAN FIROOZABADI, AHMAD BITARAFAN RAJABI, MAJID HAGHJOO, AHMAD AMIN, NASRIN AZIZIAN, and FERIDOON RASTGOU, “COMPARISON OF GATED SPECT MYOCARDIAL PERFUSION IMAGING WITH ECHOCARDIOGRAPHY FOR THE MEASUREMENT OF LEFT VENTRICULAR VOLUMES AND EJECTION FRACTION IN PATIENTS WITH SEVERE HEART FAILURE,” RESEARCH IN CARDIOVASCULAR MEDICINE, vol. 5, no. 1, pp. 0–0, 2016, [Online]. Available: https://sid.ir/paper/346923/en

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