IN VITRO ASSESSMENT OF THE PROTOSCOLICIDAL ACTIVITIES OF THE EPHEDRA MAJOR METHANOL EXTRACTS

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ZIBAEI MOHAMMAD; SALEHI SEPIDEH; JAFARI ZOHREH; BAHADORY SAEED; FIROOZEH FARZANEH; SHAHIVAND MEHDI

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Journal: International Journal of Enteric Pathogens Year:2017 | Volume:5 | Issue:1 Page(s): 5-8

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Title

IN VITRO ASSESSMENT OF THE PROTOSCOLICIDAL ACTIVITIES OF THE EPHEDRA MAJOR METHANOL EXTRACTS

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Keywords

ECHINOCOCCUS GRANULOSUS

EPHEDRA MAJOR

PROTOSCOLICIDAL ACTIVITY

HYDATID CYST

Abstract

Background: The basic approaches for the treatment of human hydatidosis are surgery and chemotherapy. The risk of spillage of protoscoleces cannot be underestimated during surgery.Objectives: This study aimed to evaluate the scolicidal activity of EPHEDRA MAJOR methanol extracts against protoscoleces of HYDATID CYSTs.Materials and Methods: Various concentrations of the methanolic extracts (0.01%-0.001%, mg/mL) of different parts of E. major were used for exposure times of 10, 20, 30, and 60 minutes.Results: Different extracts of E. major were tested, 0.1% concentration had strong scolicidal activity in 60 minutes. The stem extracts of 0.1% had very strong scolicidal effects in 60 minutes of exposure time and the mortality rate decreased with the lower concentration.Conclusion: Findings showed that scolicidal effects of E. major root extracts against cystic echinococcosis protoscoleces were less effective, while the stem and leaf extracts demonstrated more activities, respectively.

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APA: Copy

ZIBAEI, MOHAMMAD, SALEHI, SEPIDEH, JAFARI, ZOHREH, BAHADORY, SAEED, FIROOZEH, FARZANEH, & SHAHIVAND, MEHDI. (2017). IN VITRO ASSESSMENT OF THE PROTOSCOLICIDAL ACTIVITIES OF THE EPHEDRA MAJOR METHANOL EXTRACTS. INTERNATIONAL JOURNAL OF ENTERIC PATHOGEN, 5(1), 5-8. SID. https://sid.ir/paper/347483/en

Vancouver: Copy

ZIBAEI MOHAMMAD, SALEHI SEPIDEH, JAFARI ZOHREH, BAHADORY SAEED, FIROOZEH FARZANEH, SHAHIVAND MEHDI. IN VITRO ASSESSMENT OF THE PROTOSCOLICIDAL ACTIVITIES OF THE EPHEDRA MAJOR METHANOL EXTRACTS. INTERNATIONAL JOURNAL OF ENTERIC PATHOGEN[Internet]. 2017;5(1):5-8. Available from: https://sid.ir/paper/347483/en

IEEE: Copy

MOHAMMAD ZIBAEI, SEPIDEH SALEHI, ZOHREH JAFARI, SAEED BAHADORY, FARZANEH FIROOZEH, and MEHDI SHAHIVAND, “IN VITRO ASSESSMENT OF THE PROTOSCOLICIDAL ACTIVITIES OF THE EPHEDRA MAJOR METHANOL EXTRACTS,” INTERNATIONAL JOURNAL OF ENTERIC PATHOGEN, vol. 5, no. 1, pp. 5–8, 2017, [Online]. Available: https://sid.ir/paper/347483/en

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