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Information Journal Paper

Title

CHARACTERIZATION OF AN ANTIMICROBIAL EXTRACT FROM ELAEAGNUS ANGUSTIFOLIA

Pages

  0-0

Abstract

 Background: According to ethnobotanical data, ELAEAGNUS ANGUSTIFOLIA fruit has wound healing activity, anti-inflammatory effect and antifebrile prosperities.Objectives: This study was performed as to the best of our knowledge, there has been no scientific report on the CHARACTERIZATION of antimicrobial effect of E. angustifolia extract. Materials and Methods: An aqueous extract of ELAEAGNUS ANGUSTIFOLIA was prepared and ANTIMICROBIAL ACTIVITY tests were performed on various target cultures. Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of the extract was done using the broth dilution technique. To characterize the extract, shelf life, thermal and pH stability, effects of detergents such as Tween 80, Tween 20, Triton X100, toluene and enzymes on the ANTIMICROBIAL ACTIVITY of ELAEAGNUS ANGUSTIFOLIA extract, were examined.Results: The MIC values ranged from 7.5 to 0.1 mg/mL, showing maximum activity (1.62 mg/mL) against E. coli. Similarly, the MBC of the extract against E. coli was 1.62 mg/mL. ANTIMICROBIAL ACTIVITY of the extract was relatively stable when kept in the refrigerator for 60 days. The ANTIMICROBIAL ACTIVITY ofELAEAGNUS ANGUSTIFOLIA extract was absolutely stable at temperatures up to 700oC. After exposure of the ELAEAGNUS ANGUSTIFOLIAextract to different pH solutions in the range of 4-10, almost 100% residual activity was found against E. coli at pH 4, 5, 6, and 7.Treatment of the extract with detergents, lipase and lysozyme eliminated its ANTIMICROBIAL ACTIVITY.Conclusions: Our study gives an indication of the presence of promising antimicrobial compounds and provides basic information about the nature of theELAEAGNUS ANGUSTIFOLIA extract. Future studies should elucidate the components responsible for ANTIMICROBIAL ACTIVITY of these extracts against target cultures.

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    APA: Copy

    DEHGHAN, MOHAMMAD HOSSEIN, SOLTANI, JAFAR, KALANTAR, ENAYATOLLAH, FARNAD, MORASSA, KAMALI NEJAD, MOHAMAD, KHODAII, ZOHREH, HATAMI, SHIVA, & Mehrabani Natanzi, Mahboobeh. (2014). CHARACTERIZATION OF AN ANTIMICROBIAL EXTRACT FROM ELAEAGNUS ANGUSTIFOLIA. INTERNATIONAL JOURNAL OF ENTERIC PATHOGEN, 2(3), 0-0. SID. https://sid.ir/paper/347559/en

    Vancouver: Copy

    DEHGHAN MOHAMMAD HOSSEIN, SOLTANI JAFAR, KALANTAR ENAYATOLLAH, FARNAD MORASSA, KAMALI NEJAD MOHAMAD, KHODAII ZOHREH, HATAMI SHIVA, Mehrabani Natanzi Mahboobeh. CHARACTERIZATION OF AN ANTIMICROBIAL EXTRACT FROM ELAEAGNUS ANGUSTIFOLIA. INTERNATIONAL JOURNAL OF ENTERIC PATHOGEN[Internet]. 2014;2(3):0-0. Available from: https://sid.ir/paper/347559/en

    IEEE: Copy

    MOHAMMAD HOSSEIN DEHGHAN, JAFAR SOLTANI, ENAYATOLLAH KALANTAR, MORASSA FARNAD, MOHAMAD KAMALI NEJAD, ZOHREH KHODAII, SHIVA HATAMI, and Mahboobeh Mehrabani Natanzi, “CHARACTERIZATION OF AN ANTIMICROBIAL EXTRACT FROM ELAEAGNUS ANGUSTIFOLIA,” INTERNATIONAL JOURNAL OF ENTERIC PATHOGEN, vol. 2, no. 3, pp. 0–0, 2014, [Online]. Available: https://sid.ir/paper/347559/en

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