RISK FACTOR ANALYSIS AMONG TRIMETHOPRIM-SULFAMETHOXAZOLE RESISTANTESCHERICHIA COLI ISOLATES

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MASAELI MILAD; FARAJI TAYYEBE; RAMAZANZADEH RASHID; MANSOURI MAJID

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Journal Paper

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Journal: International Journal of Enteric Pathogens Year:2014 | Volume:2 | Issue:3 Page(s): 0-0

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Title

RISK FACTOR ANALYSIS AMONG TRIMETHOPRIM-SULFAMETHOXAZOLE RESISTANTESCHERICHIA COLI ISOLATES

Author(s)

MASAELI MILAD | FARAJI TAYYEBE | RAMAZANZADEH RASHID | MANSOURI MAJID | Issue Writer Certificate

Keywords

ESCHERICHIA COLI

HOSPITAL

TMP-SMX

RISK FACTOR

Abstract

Background: Trimethoprim-sulfamethoxazole (TMP-SMX) can be used for treatment of several infections including respiratory, renal, and gastrointestinal tract infections, skin and wound infections, septicaemia, and other infections caused by sensitive organisms.Objectives: The aim of this study was to evaluate the RISK FACTORs for acquisition of TMP-SMX-resistant ESCHERICHIA COLI strains among HOSPITALized patients in a teaching HOSPITAL of Sanandaj, Iran.Materials and Methods: It was a case-control study on a patient, carrying a TMP-SMX-resistant E. coli strain. The control patient carried a TMP-SMX-sensitiveE. coli strain. TMP-SMX resistance was determined using disk diffusion methods.Results: Of 343 isolates, 197 (57.43%) were TMP-SMX-resistant. Using ventilator and catheter were risky for acquisition of TMP-SMX-resistant isolate (odds ratio (OR) =3.037, 95% CI=1.60-5.75, P<0.000, OR=2.93, 95% CI=1.15-7.43, P<0.013, respectively). There was significant correlation between days of staying in ward and TMP-SMX resistance (P<0.003).Conclusions: The main RISK FACTORs associated with TMP-SMX resistance were using of ventilator and catheter and days of staying in ward.There is need for more studies to evaluate the role of the factors to control the spread of drug resistance.

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APA: Copy

MASAELI, MILAD, FARAJI, TAYYEBE, RAMAZANZADEH, RASHID, & MANSOURI, MAJID. (2014). RISK FACTOR ANALYSIS AMONG TRIMETHOPRIM-SULFAMETHOXAZOLE RESISTANTESCHERICHIA COLI ISOLATES. INTERNATIONAL JOURNAL OF ENTERIC PATHOGEN, 2(3), 0-0. SID. https://sid.ir/paper/347562/en

Vancouver: Copy

MASAELI MILAD, FARAJI TAYYEBE, RAMAZANZADEH RASHID, MANSOURI MAJID. RISK FACTOR ANALYSIS AMONG TRIMETHOPRIM-SULFAMETHOXAZOLE RESISTANTESCHERICHIA COLI ISOLATES. INTERNATIONAL JOURNAL OF ENTERIC PATHOGEN[Internet]. 2014;2(3):0-0. Available from: https://sid.ir/paper/347562/en

IEEE: Copy

MILAD MASAELI, TAYYEBE FARAJI, RASHID RAMAZANZADEH, and MAJID MANSOURI, “RISK FACTOR ANALYSIS AMONG TRIMETHOPRIM-SULFAMETHOXAZOLE RESISTANTESCHERICHIA COLI ISOLATES,” INTERNATIONAL JOURNAL OF ENTERIC PATHOGEN, vol. 2, no. 3, pp. 0–0, 2014, [Online]. Available: https://sid.ir/paper/347562/en

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