A TENTATIVE STAGING OF MULTIPLE MYELOMA BY UTILIZING RESPECTIVE COEFFICIENTS OF PROGNOSTIC FACTORS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JALAEIKHOO HASAN; SHARIFZADEH MORTEZA; RAJAEINEJAD MOHSEN; KEYHANI MANOUTCHEHR; ZOKAASADI MOHAMMAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Multidisciplinary Cancer Investigation Year:2018 | Volume:2 | Issue:1 Page(s): 22-25

Download Full-Text

View:

264

Download:

140

Cites:

Information Journal Paper

Title

A TENTATIVE STAGING OF MULTIPLE MYELOMA BY UTILIZING RESPECTIVE COEFFICIENTS OF PROGNOSTIC FACTORS

Author(s)

Keywords

MULTIPLE MYELOMA

STAGING

PROGNOSTIC FACTORS

Abstract

Introduction: MULTIPLE MYELOMA is a heterogeneous disease with different survival times among patients. Accurate prediction of prognosis in MULTIPLE MYELOMA is essential, as patients with a shorter survival time may require early bone marrow transplantation (BMT) and more advanced chemotherapy as a part of their first-line treatment. In the present study, a parameter, depicted by gamma (γ) symbol, was utilized to categorize patients into different stages. Gamma value is equal to the summation of each prognostic factor multiplied by its corresponding beta coefficient. This parameter has been previously studied for the STAGING of some malignancies, such as “Nottingham Prognostic Index” for breast cancer and “Prognostic Score” for parotid carcinoma.Methods: One hundred forty-three cases were randomly divided into two groups. Beta coefficients for PROGNOSTIC FACTORS, including creatinine, calcium, and albumin, were obtained from multivariate Cox analysis in the first group. In this group, a STAGING system based on patients’ gamma parameters was defined followed by the evaluation of the accuracy of this STAGING system in the second group.Results: The STAGING system that developed from the first group was suitable for the prediction of outcomes in the second group. The patients of the second group were divided into approximately equal numbers in each stage comprising 29, 24, and 18 cases in stage 1, 2, and 3, respectively. In this group, the median overall survival (OS) values for patients in each stage were 92, 57, and 22 months, respectively, with log-rank = 0.002. Conclusions: The proposed method demonstrated promising results for myeloma prognostication. The authors believe this approach would increase the strength and validity of STAGING of MULTIPLE MYELOMA.

Cites

No record.

References

No record.

Cite

APA: Copy

JALAEIKHOO, HASAN, SHARIFZADEH, MORTEZA, RAJAEINEJAD, MOHSEN, KEYHANI, MANOUTCHEHR, & ZOKAASADI, MOHAMMAD. (2018). A TENTATIVE STAGING OF MULTIPLE MYELOMA BY UTILIZING RESPECTIVE COEFFICIENTS OF PROGNOSTIC FACTORS. MULTIDISCIPLINARY CANCER INVESTIGATION, 2(1), 22-25. SID. https://sid.ir/paper/349692/en

Vancouver: Copy

JALAEIKHOO HASAN, SHARIFZADEH MORTEZA, RAJAEINEJAD MOHSEN, KEYHANI MANOUTCHEHR, ZOKAASADI MOHAMMAD. A TENTATIVE STAGING OF MULTIPLE MYELOMA BY UTILIZING RESPECTIVE COEFFICIENTS OF PROGNOSTIC FACTORS. MULTIDISCIPLINARY CANCER INVESTIGATION[Internet]. 2018;2(1):22-25. Available from: https://sid.ir/paper/349692/en

IEEE: Copy

HASAN JALAEIKHOO, MORTEZA SHARIFZADEH, MOHSEN RAJAEINEJAD, MANOUTCHEHR KEYHANI, and MOHAMMAD ZOKAASADI, “A TENTATIVE STAGING OF MULTIPLE MYELOMA BY UTILIZING RESPECTIVE COEFFICIENTS OF PROGNOSTIC FACTORS,” MULTIDISCIPLINARY CANCER INVESTIGATION, vol. 2, no. 1, pp. 22–25, 2018, [Online]. Available: https://sid.ir/paper/349692/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops