DIAGNOSTIC UTILITY OF MIRNAS IN CANCER

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AHMAD BHAT SHOWKAT; MAJID SABHIYA; REHMAN MUNEEB U.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Multidisciplinary Cancer Investigation Year:2018 | Volume:2 | Issue:3 Page(s): 5-15

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Information Journal Paper

Title

DIAGNOSTIC UTILITY OF MIRNAS IN CANCER

Author(s)

AHMAD BHAT SHOWKAT | MAJID SABHIYA | REHMAN MUNEEB U. | Issue Writer Certificate

Keywords

MICRORNAS

BIOMARKERS

DIAGNOSIS

PROGNOSIS

Abstract

Cancer is the one of most prevalent and leading causes of death in the world. Current advancements in technology improve the understanding of the pathogenesis and pathology of cancers. But, due to enlarging mortality rates, poor PROGNOSIS, and lacunae in clinical early predictive BIOMARKERS provide an important momentum to investigate novel early diagnostic/ prognostic markers and specific targets for cancers therapeutics sufficiently sensitive to cancers. Recently, the emerging small noncoding MICRORNAS (miRNAs) are suggested as important and critical regulators in the oncogenesis pathways and serve as precise and useful early clinical BIOMARKERS. This new class of BIOMARKERS is emerging as a novel molecule for cancer DIAGNOSIS and PROGNOSIS and recent miRNA expression studies in tumors yield promising results. However, establishing miRNA expression in the blood circulation, cell-free as noninvasive marker, has advantages over determination of tumor in primary tissue. A better understanding of the involvement of this class of molecular markers in carcinogenesis could provide new insights into the mechanisms in the development of tumor and could be helpful to identify new specific novel early powerful markers for the early detection of cancer. The current review study aimed at summarizing the recent research studies supporting the utility of miRNAs as novel early diagnostic and prognostic tools, thus potentially illuminating future treatment strategies for cancers, which indicates the feasibility and clinical applications and the importance of miRNAs in cancer for researchers and clinical diagnostic centers.

Cites

Scenario and future prospects of microRNAs in gastric cancer: A review

References

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APA: Copy

AHMAD BHAT, SHOWKAT, MAJID, SABHIYA, & REHMAN, MUNEEB U.. (2018). DIAGNOSTIC UTILITY OF MIRNAS IN CANCER. MULTIDISCIPLINARY CANCER INVESTIGATION, 2(3), 5-15. SID. https://sid.ir/paper/349698/en

Vancouver: Copy

AHMAD BHAT SHOWKAT, MAJID SABHIYA, REHMAN MUNEEB U.. DIAGNOSTIC UTILITY OF MIRNAS IN CANCER. MULTIDISCIPLINARY CANCER INVESTIGATION[Internet]. 2018;2(3):5-15. Available from: https://sid.ir/paper/349698/en

IEEE: Copy

SHOWKAT AHMAD BHAT, SABHIYA MAJID, and MUNEEB U. REHMAN, “DIAGNOSTIC UTILITY OF MIRNAS IN CANCER,” MULTIDISCIPLINARY CANCER INVESTIGATION, vol. 2, no. 3, pp. 5–15, 2018, [Online]. Available: https://sid.ir/paper/349698/en

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