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Information Journal Paper

Title

DETERMINATION OF THE EFFECTS OF DIGOXIN ON THE RIGHT VENTRICULAR FUNCTION IN PATIENTS UNDERGOING PNEUMONECTOMY

Pages

  123-126

Abstract

 Introduction: PNEUMONECTOMY is the standard treatment of lung cancer, eventhough patients should undergo several evaluations before surgery; deterioration of CARDIOPULMONARY FUNCTION after pulmonary resection isinevitable. We have evaluated the effects of DIGOXIN on the improvement of rightventricular function and prevention of probable complications after lungresection surgery.Materials and Methods: All patients who were candidate for PNEUMONECTOMYor extensive lobectomy in Ghaem hospital from 2010 to 2012 were enrolledinto this study and were divided into two groups randomly. The first group(group D) received DIGOXIN during surgery and in the second group (group C)normal saline was administered as placebo. Echocardiographic evaluation of thepatients was accomplished the day before and the day after surgery.Results: Among 20 patients in each group, male to female ratio was almost 2: 1and mean age was 63.8 (ranged 46-83 years). The most common cause ofpneumonectomy was lung cancer. Comparison of the preoperative demographicvariables, blood biochemistry, pulmonary function tests, echocardiographic andblood gas indexes showed no statistically significant differences between twogroups. But postoperative evaluations showed a significant improvement in leftventricular ejection fraction in group D. Right ventricular systolic and diastolicdiameters and pulmonary artery pressure were decreased significantly as well.Conclusion: According to our results, we suggest a single dose of DIGOXIN duringlung resection surgery to improve cardiac performance after PNEUMONECTOMY.

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    APA: Copy

    SHARIFIAN ATTAR, ALIREZA, JALAEIAN TAGHADDOMI, REZA, MOUHEBATI, MOHSEN, BAGHERI, REZA, & HOSSEINIAN, ELAHE. (2014). DETERMINATION OF THE EFFECTS OF DIGOXIN ON THE RIGHT VENTRICULAR FUNCTION IN PATIENTS UNDERGOING PNEUMONECTOMY. JOURNAL OF CARDIO THORACIC MEDICINE, 2(1), 123-126. SID. https://sid.ir/paper/349747/en

    Vancouver: Copy

    SHARIFIAN ATTAR ALIREZA, JALAEIAN TAGHADDOMI REZA, MOUHEBATI MOHSEN, BAGHERI REZA, HOSSEINIAN ELAHE. DETERMINATION OF THE EFFECTS OF DIGOXIN ON THE RIGHT VENTRICULAR FUNCTION IN PATIENTS UNDERGOING PNEUMONECTOMY. JOURNAL OF CARDIO THORACIC MEDICINE[Internet]. 2014;2(1):123-126. Available from: https://sid.ir/paper/349747/en

    IEEE: Copy

    ALIREZA SHARIFIAN ATTAR, REZA JALAEIAN TAGHADDOMI, MOHSEN MOUHEBATI, REZA BAGHERI, and ELAHE HOSSEINIAN, “DETERMINATION OF THE EFFECTS OF DIGOXIN ON THE RIGHT VENTRICULAR FUNCTION IN PATIENTS UNDERGOING PNEUMONECTOMY,” JOURNAL OF CARDIO THORACIC MEDICINE, vol. 2, no. 1, pp. 123–126, 2014, [Online]. Available: https://sid.ir/paper/349747/en

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