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Information Journal Paper

Title

TRANSCATHETER AORTIC VALVE REPLACEMENT: A REVIEW ARTICLE

Pages

  423-436

Abstract

 Transcatheter AORTIC VALVE REPLACEMENT (TAVR) is a novel therapeuticintervention for the replacement of severely stenotic aortic valves in highrisk patients for standard surgical procedures. Since the initial PARTNERtrial results, use of TAVR has been on the rise each year. New deliverymethods and different valves have been developed and modified in orderto promote the minimally invasive procedure and reduce commoncomplications, such as stroke. This review article focuses on the currentdata on the indications, risks, benefits, and future directions of TAVR.Recently, TAVR has been considered as a standard-of-care procedure. Whilethis technique is used frequently in high-risk surgical candidates, studies havebeen focusing on the application of this method for younger patients withlower surgical risk. Moreover, several studies have proposed promising resultsregarding the use of valve-in-valve technique or the procedure in which thevalve is placed within a previously implemented bioprosthetic valve. However, ischemic strokes and paravalvular leak remain a matter of debate in thesesurgeries. New methods and devices have been developed to reduce theincidence of post-procedural stroke. While the third generation of TAVR valves(i.e., Edwards Sapien 3 and Medtronic Evolut R) addresses the issue ofparavalvular leak structurally, results on their efficacy in reducing the risk ofparavalvular leak are yet to be obtained. Furthermore, TAVR enters the field ofhybrid methods in the treatment of cardiac issues via both surgical andcatheter-based approaches. Finally, while TAVR is primarily performed oncases with aortic stenosis, new valves and methods have been proposedregarding the application of this technique in aortic regurgitation, as well asother aortic pathologies.TAVR is a suitable therapeutic approach for the treatment of aorticstenosis in high-risk patients. Considering the promising results in thecurrent patient population, recent studies have been conducted toevaluate the efficacy of this approach as a standard-of-care procedure.

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  • Cite

    APA: Copy

    SIORDIA, JUAN A.. (2016). TRANSCATHETER AORTIC VALVE REPLACEMENT: A REVIEW ARTICLE. JOURNAL OF CARDIO THORACIC MEDICINE, 4(2), 423-436. SID. https://sid.ir/paper/349798/en

    Vancouver: Copy

    SIORDIA JUAN A.. TRANSCATHETER AORTIC VALVE REPLACEMENT: A REVIEW ARTICLE. JOURNAL OF CARDIO THORACIC MEDICINE[Internet]. 2016;4(2):423-436. Available from: https://sid.ir/paper/349798/en

    IEEE: Copy

    JUAN A. SIORDIA, “TRANSCATHETER AORTIC VALVE REPLACEMENT: A REVIEW ARTICLE,” JOURNAL OF CARDIO THORACIC MEDICINE, vol. 4, no. 2, pp. 423–436, 2016, [Online]. Available: https://sid.ir/paper/349798/en

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