COMPARISON OF TREATMENT OUTCOMES IN OFF-PUMP CORONARY ARTERY BYPASS GRAFT AND MEDICAL THERAPY IN PATIENTS WITH TRIPLE-VESSEL CORONARY ARTERY DISEASE AND SEVERE VENTRICULAR DYSFUNCTION

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SABZI FERIDOUN

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Journal Paper

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Journal: JOURNAL OF CARDIO THORACIC MEDICINE Year:2016 | Volume:4 | Issue:2 Page(s): 450-455

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Title

COMPARISON OF TREATMENT OUTCOMES IN OFF-PUMP CORONARY ARTERY BYPASS GRAFT AND MEDICAL THERAPY IN PATIENTS WITH TRIPLE-VESSEL CORONARY ARTERY DISEASE AND SEVERE VENTRICULAR DYSFUNCTION

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SABZI FERIDOUN | Issue Writer Certificate

Keywords

CORONARY ARTERY DISEASE

MEDICAL THERAPY

OFF-PUMP CORONARY ARTERY BYPASS

GRAF

Abstract

Introduction: Heart failure is a major hazard for public health. Despite recent advance inmedical therapy, there is not enough information on the outcome of off-pump coronaryartery bypass (OPCAB) and MEDICAL THERAPY on the patients with severe ventriculardysfunction and triple-vessel (CAD). This study aimed to compare treatment outcomesand mortality rate in patients undergoing OFF-PUMP CORONARY ARTERY BYPASS (OPCAB)surgery and MEDICAL THERAPY who presented with severe ventricular dysfunction andtriple-vessel CORONARY ARTERY DISEASE (CAD).Materials and Methods: This retrospective cohort study was conducted on patients withsevere ventricular dysfunction and triple-vessel CAD during 2010-2011 in the Imam AliHospital of Kermanshah University of Medical Science. Patients were divided into twogroups of MEDICAL THERAPY (group one) and OPCAB (group two). Follow-up data werecollected after 30 months. Survival estimation was performed using Kaplan-Meiersurvival analysis and Cox regression model.Results: Of the 276 enrolled patients, 139 (50.4%) underwent group one and 137 (49.6%)group two. Study groups were homogenous in baseline characteristics, with the exceptionof hyperlipidemia (P=0.005). A significant difference was observed in cardiac mortalityrates between the study groups (hazard ratio: 0.260; 95% confidence interval: 0.105-0.644; P=0.004). However, no significant difference was observed between the groupsregarding the frequency of admission due to decompensate heart failure (P=0.17). Inaddition, the rate of admission due to acute coronary syndrome (ACS) in the first groupwas higher than the second group, significantly (P=0.001). Level of ejection fraction (EF)had a significant increase after coronary artery bypass GRAFt (CABG) (28.50) compared tothe preoperative stage (27.59) (P=0.042). However, no significant increase in the level ofEF was observed in the first group before and after MEDICAL THERAPY (27.28 and 27.20, respectively) (P=0.83).Conclusion: According to the results of this study, the mortality rate associated withOPCAB was lower compared to MEDICAL THERAPY, ACS and EF enhancement in patientswith triple-vessel CAD and severe ventricular dysfunction.

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APA: Copy

SABZI, FERIDOUN. (2016). COMPARISON OF TREATMENT OUTCOMES IN OFF-PUMP CORONARY ARTERY BYPASS GRAFT AND MEDICAL THERAPY IN PATIENTS WITH TRIPLE-VESSEL CORONARY ARTERY DISEASE AND SEVERE VENTRICULAR DYSFUNCTION. JOURNAL OF CARDIO THORACIC MEDICINE, 4(2), 450-455. SID. https://sid.ir/paper/349800/en

Vancouver: Copy

SABZI FERIDOUN. COMPARISON OF TREATMENT OUTCOMES IN OFF-PUMP CORONARY ARTERY BYPASS GRAFT AND MEDICAL THERAPY IN PATIENTS WITH TRIPLE-VESSEL CORONARY ARTERY DISEASE AND SEVERE VENTRICULAR DYSFUNCTION. JOURNAL OF CARDIO THORACIC MEDICINE[Internet]. 2016;4(2):450-455. Available from: https://sid.ir/paper/349800/en

IEEE: Copy

FERIDOUN SABZI, “COMPARISON OF TREATMENT OUTCOMES IN OFF-PUMP CORONARY ARTERY BYPASS GRAFT AND MEDICAL THERAPY IN PATIENTS WITH TRIPLE-VESSEL CORONARY ARTERY DISEASE AND SEVERE VENTRICULAR DYSFUNCTION,” JOURNAL OF CARDIO THORACIC MEDICINE, vol. 4, no. 2, pp. 450–455, 2016, [Online]. Available: https://sid.ir/paper/349800/en

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