Association Between 50 bp Insertion/Deletion Polymorphism in Promoter of the Superoxide Dismutase-1 and Temperament

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ZENDEHBOODI ZAHRA

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Journal Paper

Paper Information

Journal: International Journal of Basic Science in Medicine Year:2018 | Volume:3 | Issue:2 Page(s): 59-62

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Title

Association Between 50 bp Insertion/Deletion Polymorphism in Promoter of the Superoxide Dismutase-1 and Temperament

Author(s)

ZENDEHBOODI ZAHRA | Issue Writer Certificate

Keywords

Temperament

Superoxide dismutase-1

Polymorphism

Abstract

Introduction: Temperament (mizaj) plays an important role in society’ s general health as well as in diagnosis and treatment of diseases. Despite its effectiveness, the mechanisms of Temperament-dependent treatment in practical Iranian Traditional Medicine (ITM) has not been well understood yet. This study aimed to evaluate the association between the Temperament and Superoxide dismutase-1 (SOD1) Polymorphism. Methods: The study was carried out on healthy blood donors. All participants were from Fars province, southern Iran. To determine the participants’ Temperaments, a self-reported identification scale was used. Two hundred eighty males with any of 4 simple Temperaments (Warm, Cold, Moist, and Dry) were included. The SOD1 genotypes were determined using a polymerase chain reaction (PCR)-based method. Multinomial logistic regression was used to calculate odds ratios (ORs) and 95% CI for the association of Temperament with SOD1 Polymorphism. Results: No association was found between the insertion/deletion (Ins/Del) Polymorphism of SOD1 and each of the Temperament groups. Conclusion: The results of this study indicated that the Temperament is not affected by the Ins/ Del Polymorphism of SOD1. Further research with larger samples and with other genes of antioxidant system is recommended.

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APA: Copy

ZENDEHBOODI, ZAHRA. (2018). Association Between 50 bp Insertion/Deletion Polymorphism in Promoter of the Superoxide Dismutase-1 and Temperament. INTERNATIONAL JOURNAL OF BASIC SCIENCE IN MEDICINE, 3(2), 59-62. SID. https://sid.ir/paper/350705/en

Vancouver: Copy

ZENDEHBOODI ZAHRA. Association Between 50 bp Insertion/Deletion Polymorphism in Promoter of the Superoxide Dismutase-1 and Temperament. INTERNATIONAL JOURNAL OF BASIC SCIENCE IN MEDICINE[Internet]. 2018;3(2):59-62. Available from: https://sid.ir/paper/350705/en

IEEE: Copy

ZAHRA ZENDEHBOODI, “Association Between 50 bp Insertion/Deletion Polymorphism in Promoter of the Superoxide Dismutase-1 and Temperament,” INTERNATIONAL JOURNAL OF BASIC SCIENCE IN MEDICINE, vol. 3, no. 2, pp. 59–62, 2018, [Online]. Available: https://sid.ir/paper/350705/en

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