EVALUATION OF THE COAGULANT EFFECT OF THE ZANJANI AND LATIFI VIPER VENOM ENDEMIC IN IRAN

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TAHERIAN MILAD; YAGHOOBI HAJAR; BANDEHPOUR MOJGAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Trends in Peptide and Protein Sciences Year:2016 | Volume:1 | Issue:1 Page(s): 27-30

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Title

EVALUATION OF THE COAGULANT EFFECT OF THE ZANJANI AND LATIFI VIPER VENOM ENDEMIC IN IRAN

Author(s)

TAHERIAN MILAD | YAGHOOBI HAJAR | BANDEHPOUR MOJGAN | Issue Writer Certificate

Keywords

LATIFI VIPER

ZANJANI VIPER

SDS-PAGE

PTT

APTT

Abstract

The venom of the viper is very important in pharmaceutical usage, such as in the process of coagulation during medical care. This study aims to evaluate the coagulant factor of Latifi and ZANJANI VIPER venom. In the current study, after electrophoresis of proteins found in viper venom, all of the thick and strong bands of proteins were isolated and prepared for examination of coagulation characteristics, like pro-thrombin time (PTT) and active partial thromboplastic time (APTT), followed by further study by mass spectroscopy. In this way, 11 bands of proteins were recognized in sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE). After PT and APTT tests, one common band in 26 KDa could lead to coagulation of blood plasma in less than one second. Mass spectroscopy identified this band as serine protease isoform4. The results confirmed the coagulation effect of a 26 KDa protein fraction of venom from Latifi and ZANJANI VIPERs.

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APA: Copy

TAHERIAN, MILAD, YAGHOOBI, HAJAR, & BANDEHPOUR, MOJGAN. (2016). EVALUATION OF THE COAGULANT EFFECT OF THE ZANJANI AND LATIFI VIPER VENOM ENDEMIC IN IRAN. TRENDS IN PEPTIDE AND PROTEIN SCIENES, 1(1), 27-30. SID. https://sid.ir/paper/350786/en

Vancouver: Copy

TAHERIAN MILAD, YAGHOOBI HAJAR, BANDEHPOUR MOJGAN. EVALUATION OF THE COAGULANT EFFECT OF THE ZANJANI AND LATIFI VIPER VENOM ENDEMIC IN IRAN. TRENDS IN PEPTIDE AND PROTEIN SCIENES[Internet]. 2016;1(1):27-30. Available from: https://sid.ir/paper/350786/en

IEEE: Copy

MILAD TAHERIAN, HAJAR YAGHOOBI, and MOJGAN BANDEHPOUR, “EVALUATION OF THE COAGULANT EFFECT OF THE ZANJANI AND LATIFI VIPER VENOM ENDEMIC IN IRAN,” TRENDS IN PEPTIDE AND PROTEIN SCIENES, vol. 1, no. 1, pp. 27–30, 2016, [Online]. Available: https://sid.ir/paper/350786/en

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