Formulation and Evaluation of Langsat (Lansium domesticum Corr. ) Peel Ethanol extracts Lotion as Anti-Mosquito Repellent

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Hiola Rama; Rizky Nurul; Hasan Hamsidar; Thomas Nurain

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Journal: JOURNAL OF REPORTS IN PHARMACEUTICAL SCIENCES Year:2018 | Volume:7 | Issue:3 Page(s): 250-259

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Title

Formulation and Evaluation of Langsat (Lansium domesticum Corr. ) Peel Ethanol extracts Lotion as Anti-Mosquito Repellent

Author(s)

Hiola Rama | Rizky Nurul | Hasan Hamsidar | Thomas Nurain | Issue Writer Certificate

Keywords

Langsat Peel

Ethanol Extract

Repellent

Lotion

Abstract

The Repellent is a material that works in protecting humans from mosquito bites. Langsat Peel (Lansium domesticum Corr. ) is one of the plants having function as Repellent, anti-mosquito containing triterpenoid compound. The purpose of this research was to formulate the Langsat Peel Ethanol Extract into anti-mosquito Lotion and to determine the effectiveness of Repellent anti-mosquito from the best formulation of the Langsat Peel Ethanol Extract. The Optimization of the Lotion basis was performed on three variations of cetyl alcohol concentrations i. e. 3%, 5%, and 7% respectively and obtained F2 containing 5% Cetyl alcohol as the optimum base. The F2 Lotion basis formula was formulated into Lotion with three concentrations of 10%, 20%, and 35%. The three Lotions formula of the Langsat Peel Ethanol Extract was tested by organoleptic test, preparation, spreading test, adhesion test and stability test, including pH and viscosity exposed at 15-30oC, 4oC and 40oC. All formulas were tested for irritation using rabbits for 3 days and did not show any erythema and edema. Tests of the effectiveness of anti-mosquito were done on rabbit using mosquitoes. The results obtained showed that Langsat Peel extract 20% and 35% had effectiveness as anti-mosquito Repellent and can be formulated into Lotion dosage form.

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APA: Copy

Hiola, Rama, Rizky, Nurul, Hasan, Hamsidar, & Thomas, Nurain. (2018). Formulation and Evaluation of Langsat (Lansium domesticum Corr. ) Peel Ethanol extracts Lotion as Anti-Mosquito Repellent. JOURNAL OF REPORTS IN PHARMACEUTICAL SCIENCES, 7(3), 250-259. SID. https://sid.ir/paper/354660/en

Vancouver: Copy

Hiola Rama, Rizky Nurul, Hasan Hamsidar, Thomas Nurain. Formulation and Evaluation of Langsat (Lansium domesticum Corr. ) Peel Ethanol extracts Lotion as Anti-Mosquito Repellent. JOURNAL OF REPORTS IN PHARMACEUTICAL SCIENCES[Internet]. 2018;7(3):250-259. Available from: https://sid.ir/paper/354660/en

IEEE: Copy

Rama Hiola, Nurul Rizky, Hamsidar Hasan, and Nurain Thomas, “Formulation and Evaluation of Langsat (Lansium domesticum Corr. ) Peel Ethanol extracts Lotion as Anti-Mosquito Repellent,” JOURNAL OF REPORTS IN PHARMACEUTICAL SCIENCES, vol. 7, no. 3, pp. 250–259, 2018, [Online]. Available: https://sid.ir/paper/354660/en

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