EFFECTS OF ORAL MORPHINE CONSUMPTION DURING PREGNANCY ON RETINA DEVELOPMENT OF THE WISTAR RAT EMBRYO

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

TEKIEH E.; RAMEZANI MINA; ZARDOUZ H.; GOLMANESH L.; BAHADORAN H.; SAHRAEI HEDAYAT

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Koomesh Year:2010 | Volume:12 | Issue:1 (37) Page(s): 79-86

Download Full-Text

Persian Verion

View:

1,042

Download:

Cites:

Information Journal Paper

Title

EFFECTS OF ORAL MORPHINE CONSUMPTION DURING PREGNANCY ON RETINA DEVELOPMENT OF THE WISTAR RAT EMBRYO

Author(s)

Keywords

VISUAL SYSTEMQ3

DEVELOPMENTQ2

RETINAQ2

MORPHINEQ2

EMBRYOQ2

RATQ2

Abstract

Introduction: VISUAL SYSTEM is composed from different parts with different EMBRYOnic origins. In the present study, the effect of oral MORPHINE consumption on RETINA DEVELOPMENT of the Wistar RAT EMBRYO was investigated.Material and Methods: 40 female Wistar RATs (250-300 g) were used. After mating, the EMBRYOnic zero day (E0) was determined and then the pregnant females were divided randomly into experimental or control groups. Controls received tap water whereas experiments received MORPHINE (0.05 mg/ml) in their waters. On the E17, pregnant females were killed and EMBRYOs were removed and kept in formalin 10% for 30 days. Then, heads of the EMBRYOs were dissected and processed by routine procedures. Sagittal sections of 5um were stained with haematoxylin– eosin and examined by using a light microscope and the Motic soft ware.Results: The RETINAl diameter was reduced in the experimental group. In addition, the granular and neural layers were fully developed in the control group, but they showed delayed DEVELOPMENTs in the experimental group. At last, there were empty pores between cells in the experimental group. Moreover, the plasma corticosterone levels were increased in the experimental group.Conclusion: These results indicated that oral MORPHINE consumption during pregnancy may induce defects in RETINA DEVELOPMENT in the RAT EMBRYO. This may be related to an increased in the plasma corticosterone levels.

Cites

No record.

References

Cite

APA: Copy

TEKIEH, E., RAMEZANI, MINA, ZARDOUZ, H., GOLMANESH, L., BAHADORAN, H., & SAHRAEI, HEDAYAT. (2010). EFFECTS OF ORAL MORPHINE CONSUMPTION DURING PREGNANCY ON RETINA DEVELOPMENT OF THE WISTAR RAT EMBRYO. KOOMESH, 12(1 (37)), 79-86. SID. https://sid.ir/paper/356985/en

Vancouver: Copy

TEKIEH E., RAMEZANI MINA, ZARDOUZ H., GOLMANESH L., BAHADORAN H., SAHRAEI HEDAYAT. EFFECTS OF ORAL MORPHINE CONSUMPTION DURING PREGNANCY ON RETINA DEVELOPMENT OF THE WISTAR RAT EMBRYO. KOOMESH[Internet]. 2010;12(1 (37)):79-86. Available from: https://sid.ir/paper/356985/en

IEEE: Copy

E. TEKIEH, MINA RAMEZANI, H. ZARDOUZ, L. GOLMANESH, H. BAHADORAN, and HEDAYAT SAHRAEI, “EFFECTS OF ORAL MORPHINE CONSUMPTION DURING PREGNANCY ON RETINA DEVELOPMENT OF THE WISTAR RAT EMBRYO,” KOOMESH, vol. 12, no. 1 (37), pp. 79–86, 2010, [Online]. Available: https://sid.ir/paper/356985/en

Related Journal Papers