MEASUREMENT OF LEVELS OF EBSTEIN-BARR VIRUS
ANTIBODIES IN PATIENTS WITH HODGKINS LYMPHOMA AND
COMPARISON WITH NORMAL POPULATION

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TAGHIPOUR SH.; MORTAZAVI ZADE S.M.R.

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Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2004 | Volume:12 | Issue:2 Page(s): 3-3

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Title

MEASUREMENT OF LEVELS OF EBSTEIN-BARR VIRUS ANTIBODIES IN PATIENTS WITH HODGKINS LYMPHOMA AND COMPARISON WITH NORMAL POPULATION

Author(s)

TAGHIPOUR SH. | MORTAZAVI ZADE S.M.R. | Issue Writer Certificate

Keywords

HODGKIN LYMPHOMAQ3

EPSTEIN-BARR VIRUS (EBV)Q3

ANTI VIRAL CAPSID ANTIGENQ4

Abstract

Introduction: Hodgkins lymphoma is a unique malignancy with unknown etiology .Curability and prognosis of Hodgkin,s disease (lID) depends on quickly early diagnosis .One of hypothesis proposed for the cause of this disease is Epstein- Barr virus infection and its activity in HD patients. Material and Methods:This case- control study was performed to determine the type and titers of antibodies against EBV capsid Antigens (Anti VCA IgM & IgG) in HD patients as compared to the general population and its relation to age, sex, and subtype of Hodgkin. Thus, a fifty- person group of Hodgkin disease patients as the case group and a fifty - person group from the general population with the same age and sex cbaracteristicsas the control group were studied. Result: There was no significant difference for mean titer ofIgM between two age ranges in each group of case and control. Also, there was statistically no significant difference between case and control groups (P.Value=0.558 ).Most of the. patients as well:as non affected persons had negative IgM titers. Regarding IgG, there was statistically no significant difference between case and control groups for being either negative or positive, and most persons (92%) of each group and were positive for IgG, but mean titer of IgG was 2.87 mmol/lit incase group and 1.50 mmol/lit in control group, and this difference between two groups was statistically significant (pvalue =0.0001). Conclusion: High titer of Anti-VCA IgG in Hodgkin disease patients compared to general population as seen in this study can explain over activity ofEBV in Hodgkins disease patients and the probable role of EBV in establishment and/or activity of the disease.

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APA: Copy

TAGHIPOUR, SH., & MORTAZAVI ZADE, S.M.R.. (2004). MEASUREMENT OF LEVELS OF EBSTEIN-BARR VIRUS ANTIBODIES IN PATIENTS WITH HODGKINS LYMPHOMA AND COMPARISON WITH NORMAL POPULATION. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 12(2), 3-3. SID. https://sid.ir/paper/35758/en

Vancouver: Copy

TAGHIPOUR SH., MORTAZAVI ZADE S.M.R.. MEASUREMENT OF LEVELS OF EBSTEIN-BARR VIRUS ANTIBODIES IN PATIENTS WITH HODGKINS LYMPHOMA AND COMPARISON WITH NORMAL POPULATION. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2004;12(2):3-3. Available from: https://sid.ir/paper/35758/en

IEEE: Copy

SH. TAGHIPOUR, and S.M.R. MORTAZAVI ZADE, “MEASUREMENT OF LEVELS OF EBSTEIN-BARR VIRUS ANTIBODIES IN PATIENTS WITH HODGKINS LYMPHOMA AND COMPARISON WITH NORMAL POPULATION,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 12, no. 2, pp. 3–3, 2004, [Online]. Available: https://sid.ir/paper/35758/en

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