THE EFFECT OF ELECTRICAL LESION OF PARAGIGANTOCELLULARIS LATERALIS NUCLEUS ON ACUTE PAIN PERCEPTION IN PRESENCE OF CLONIDINE (Α2 ADRENERGIC AGONIST) IN RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FATHI MOGHADAM H.; KESMATI M.; REZAEI SADEGH; MOHAMMADPOUR KARGAR HOSSEIN

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Basic Medical Sciences Year:2004 | Volume:7 | Issue:2 (22) Page(s): 3-6

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

754

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF ELECTRICAL LESION OF PARAGIGANTOCELLULARIS LATERALIS NUCLEUS ON ACUTE PAIN PERCEPTION IN PRESENCE OF CLONIDINE (Α2 ADRENERGIC AGONIST) IN RAT

Author(s)

FATHI MOGHADAM H. | KESMATI M. | REZAEI SADEGH | MOHAMMADPOUR KARGAR HOSSEIN | Issue Writer Certificate

Keywords

PARAGIGANTOCELLULARIS LATERALIS NUCLEUSQ2

CLONIDINEQ3

PAINQ2

Α2 ADRENERGICQ4

WITHDRAWAL SYNDROMEQ3

Abstract

PARAGIGANTOCELLULARIS LATERALIS NUCLEUS (LPGi) involves several functions such as cardiovascular regulation, sexual behavior, WITHDRAWAL SYNDROME and. PAIN. In addition, the role of Α2 ADRENERGIC in analgesia has been reported as well. We studied the role of Α2 ADRENERGIC receptor in LPGi on acute PAIN. After surgical process LPGi was lesioned bilaterally by using electrical DC current (1mA, 6 second), at stereotaxic coordinates of (AP=11.8, Lat±1.86 and Depth=10.5). PAIN perception was tested using a standard hot plate. No significant difference was found between the control group and the sham group. There is a significant difference between the sham group and lesion+saline group (P<0.0002). There are significant differences between the lesion+saline group and lesion+0.02 mg/km CLONIDINE (P<0.001) as well as lesion+saline group and lesion+0.2mg/km CLONIDINE (P<0.001). We conclude that Α2 ADRENERGIC receptors of LPGi nucleus not only have a major role in the CLONIDINEinduced analgesia but also may be affecting other parts of CNS to induce analgesia in rat.

Cites

No record.

References

No record.

Cite

APA: Copy

FATHI MOGHADAM, H., KESMATI, M., REZAEI, SADEGH, & MOHAMMADPOUR KARGAR, HOSSEIN. (2004). THE EFFECT OF ELECTRICAL LESION OF PARAGIGANTOCELLULARIS LATERALIS NUCLEUS ON ACUTE PAIN PERCEPTION IN PRESENCE OF CLONIDINE (Α2 ADRENERGIC AGONIST) IN RAT. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 7(2 (22)), 3-6. SID. https://sid.ir/paper/358745/en

Vancouver: Copy

FATHI MOGHADAM H., KESMATI M., REZAEI SADEGH, MOHAMMADPOUR KARGAR HOSSEIN. THE EFFECT OF ELECTRICAL LESION OF PARAGIGANTOCELLULARIS LATERALIS NUCLEUS ON ACUTE PAIN PERCEPTION IN PRESENCE OF CLONIDINE (Α2 ADRENERGIC AGONIST) IN RAT. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2004;7(2 (22)):3-6. Available from: https://sid.ir/paper/358745/en

IEEE: Copy

H. FATHI MOGHADAM, M. KESMATI, SADEGH REZAEI, and HOSSEIN MOHAMMADPOUR KARGAR, “THE EFFECT OF ELECTRICAL LESION OF PARAGIGANTOCELLULARIS LATERALIS NUCLEUS ON ACUTE PAIN PERCEPTION IN PRESENCE OF CLONIDINE (Α2 ADRENERGIC AGONIST) IN RAT,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 7, no. 2 (22), pp. 3–6, 2004, [Online]. Available: https://sid.ir/paper/358745/en

Related Journal Papers