EVALUATION OF SUBACUTE TOXICITY OF AQUEOUS EXTRACT OF CROCUS SATIVUS L. STIGMA AND PETAL IN RATS

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KARIMI GH.; TAIEBI N.; HOSSEINZADEH A.; SHIRZAD F.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Journal of Medicinal Plants Year:2004 | Volume:3 | Issue:12 Page(s): 71-71

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Title

EVALUATION OF SUBACUTE TOXICITY OF AQUEOUS EXTRACT OF CROCUS SATIVUS L. STIGMA AND PETAL IN RATS

Author(s)

KARIMI GH. | TAIEBI N. | HOSSEINZADEH A. | SHIRZAD F. | Issue Writer Certificate

Keywords

CROCUS SATIVUSQ3

STIGMA AND PETALQ4

AQUEOUS EXTRACTQ3

SUBACUTE TOXICITYQ3

Abstract

The SUBACUTE TOXICITY of AQUEOUS EXTRACT of CROCUS SATIVUS STIGMA AND PETAL were studied in rats. Separate groups of animals were given daily intraperitoneal doses of AQUEOUS EXTRACT of stigma (0.16, 0.32 and 0.48 g/kg) and petal (1.2, 2.4 and 3.6 g/kg) for two weeks. Blood samples and selected organs were prepared for biochemical, hematological and histopathological experiments. Significant reduction of RBC, HCT and Hb were recorded with all doses of two extracts. Stigma extract did not have any deleterious effect on organs. However, petal extract induced necrosis in liver and lung cells. The results indicated that petal and stigma extracts caused normochromic normocytic anemia and petal extract induced toxic effects on liver and lung.

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APA: Copy

KARIMI, GH., TAIEBI, N., HOSSEINZADEH, A., & SHIRZAD, F.. (2004). EVALUATION OF SUBACUTE TOXICITY OF AQUEOUS EXTRACT OF CROCUS SATIVUS L. STIGMA AND PETAL IN RATS. JOURNAL OF MEDICINAL PLANTS, 3(12), 71-71. SID. https://sid.ir/paper/359302/en

Vancouver: Copy

KARIMI GH., TAIEBI N., HOSSEINZADEH A., SHIRZAD F.. EVALUATION OF SUBACUTE TOXICITY OF AQUEOUS EXTRACT OF CROCUS SATIVUS L. STIGMA AND PETAL IN RATS. JOURNAL OF MEDICINAL PLANTS[Internet]. 2004;3(12):71-71. Available from: https://sid.ir/paper/359302/en

IEEE: Copy

GH. KARIMI, N. TAIEBI, A. HOSSEINZADEH, and F. SHIRZAD, “EVALUATION OF SUBACUTE TOXICITY OF AQUEOUS EXTRACT OF CROCUS SATIVUS L. STIGMA AND PETAL IN RATS,” JOURNAL OF MEDICINAL PLANTS, vol. 3, no. 12, pp. 71–71, 2004, [Online]. Available: https://sid.ir/paper/359302/en

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