Common herbal treatments for senile dementia in ancient civilizations: Greco-Roman, Chinese, Indian, and Iranian

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AHMADIAN ATTARI MOHAMMAD MAHDI; Eslami Solat; DARGAHI LEILA; NOORBALA AHMAD ALI

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Journal Paper

Paper Information

Journal: Journal of Medicinal Plants Year:2020 | Volume:19 | Issue:73 Page(s): 37-62

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Title

Common herbal treatments for senile dementia in ancient civilizations: Greco-Roman, Chinese, Indian, and Iranian

Author(s)

AHMADIAN ATTARI MOHAMMAD MAHDI | Eslami Solat | DARGAHI LEILA | NOORBALA AHMAD ALI | Issue Writer Certificate

Keywords

Senile dementiaQ1

Alzheimer's diseaseQ2

Traditional medicineQ2

Natural productsQ2

Evidence-based phytotherapyQ1

Abstract

Background: Senile dementia is the most common kind of dementia with considerable social and economic costs. Since the nature of disease is multipathological, current treatments cannot cover all aspects of the disease. Recently, scientific considerations have focused on the role of Natural products, especially those with traditional backgrounds. Objective: to review natural treatments of dementia in ancient Greek, traditional Chinese, Ayurveda, and Iranian Traditional medicines with concentration on common herbs concurrently mentioned in two or more than two of them. Methods: Scopus database and primary sources were thoroughly searched for selective keywords. The common herbs concurrently mentioned in two or more than two of the aforementioned Traditional medicines were selected to deeply investigate for their active ingredients as well as their mechanisms of actions. Results: The results showed that Acorus calamus, Nardostachys jatamansi, Glycyrrhiza glabra, Phyllanthus emblica, Semencarpus anacardium, Terminalia chebula, and Zingiber officinale had been commonly prescribed for dementia in mentioned traditional systems. According to pharmacological studies, these herbs act their anti-dementia effects via cholinergic, anti-NMDA, antioxidant, anti-inflammatory, anti-apoptotic, and anti-β amyloid activities. Furthermore, 16 active principles of these herbs were identified, including α-and β-asarone, desoxo-narchinol A, narchinol B, glabridin, liquiritigenin, emblicanins A and B, 3, 5, 6, 3', 5', 6'-hexahydroxybiphenyl-2, 2'-dicarboxylic acid, 1', 2'-dihydroxy-3'-pentadec-8-enylbenzene, 1', 2'-dihydroxy-3'-pentadeca-8, 11-dienylbenzene, chebulagic acid, and 1, 2, 3, 4, 6-penta-O-galloyl-β-d-glucose, Zingipain, 6-gingerol, and 6-shogaol. Conclusion: Chinese, Indian, and Iranian Traditional medicine can play a complementary and alternative role in preventing and treating Senile dementia. The scientific evidence supports their traditional anti-dementia claims.

Cites

Recommended natural products in Alzheimer's disease based on traditional Persian medicine (Review Article)

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APA: Copy

AHMADIAN ATTARI, MOHAMMAD MAHDI, Eslami, Solat, DARGAHI, LEILA, & NOORBALA, AHMAD ALI. (2020). Common herbal treatments for senile dementia in ancient civilizations: Greco-Roman, Chinese, Indian, and Iranian. JOURNAL OF MEDICINAL PLANTS, 19(73 ), 37-62. SID. https://sid.ir/paper/359900/en

Vancouver: Copy

AHMADIAN ATTARI MOHAMMAD MAHDI, Eslami Solat, DARGAHI LEILA, NOORBALA AHMAD ALI. Common herbal treatments for senile dementia in ancient civilizations: Greco-Roman, Chinese, Indian, and Iranian. JOURNAL OF MEDICINAL PLANTS[Internet]. 2020;19(73 ):37-62. Available from: https://sid.ir/paper/359900/en

IEEE: Copy

MOHAMMAD MAHDI AHMADIAN ATTARI, Solat Eslami, LEILA DARGAHI, and AHMAD ALI NOORBALA, “Common herbal treatments for senile dementia in ancient civilizations: Greco-Roman, Chinese, Indian, and Iranian,” JOURNAL OF MEDICINAL PLANTS, vol. 19, no. 73 , pp. 37–62, 2020, [Online]. Available: https://sid.ir/paper/359900/en

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