Effects of Combined Exercise (aerobic + resistance) on the Expression of miR-301a and some Indicators of Motor Function in Women with Multiple Sclerosis (MS)

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Yousefi Saqqezi S.; AZAMIAN JAZI A.; HEMMATI R.; JIVAD N.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ADVANCED BIOMEDICAL SCIENCES Year:2019 | Volume:9 | Issue:2 Page(s): 1474-1486

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

546

Download:

Cites:

Information Journal Paper

Title

Effects of Combined Exercise (aerobic + resistance) on the Expression of miR-301a and some Indicators of Motor Function in Women with Multiple Sclerosis (MS)

Author(s)

Yousefi Saqqezi S. | AZAMIAN JAZI A. | HEMMATI R. | JIVAD N. | Issue Writer Certificate

Keywords

MSQ2

combined exerciseQ1

miR-301aQ1

Motor functionQ1

EDSSQ1

Abstract

Background & Objective: Several evidence has indicated the effective role of exercise on Multiple sclerosis (MS) patients. An aberrant expression of some Micro-RNAs such as increasing miR-301a in MS, with an impact on inflammatory pathways leading to the creation of inflammation in these patients. The purpose of this study was to investigate the effect of a combined eight-week (aerobic and resistance) exercise on expression of miR-301a and some indicators of Motor function in women with multiple sclerosis. Materials & Methods: A total of 22 women with MS, who were randomly divided into experimental and control groups, participated in this study. The experimental group performed 8 weeks (4 days per week) of combined training. Expression of miR-301a was measured before and after the training period using Real-Time PCR method. Pre-and post-intervention scores of tests (TUG), (6MWT), (10– MWT) and status scale (EDSS) were independent t-test recorded and analyzed. Results: The results of this study showed, the expression of miR-301a was significantly different between the two groups (P = 0. 001). Tests TUG (P = 0. 001), 6MWT (P = 0. 002) and degree of disability EDSS (P = 0. 015), were significantly different between the two groups. There was no significant difference between the 10MWT test between the two group (P = 0. 678). Conclusion: The combined exercise for women with MS have been beneficial and improve Motor function and reduce the expression of miR-301a. So, do it, plays an important role in reducing inflammation and prevent the progression of the disease MS.

Cites

No record.

References

Cite

APA: Copy

Yousefi Saqqezi, S., AZAMIAN JAZI, A., HEMMATI, R., & JIVAD, N.. (2019). Effects of Combined Exercise (aerobic + resistance) on the Expression of miR-301a and some Indicators of Motor Function in Women with Multiple Sclerosis (MS). JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, 9(2 ), 1474-1486. SID. https://sid.ir/paper/361962/en

Vancouver: Copy

Yousefi Saqqezi S., AZAMIAN JAZI A., HEMMATI R., JIVAD N.. Effects of Combined Exercise (aerobic + resistance) on the Expression of miR-301a and some Indicators of Motor Function in Women with Multiple Sclerosis (MS). JOURNAL OF ADVANCED BIOMEDICAL SCIENCES[Internet]. 2019;9(2 ):1474-1486. Available from: https://sid.ir/paper/361962/en

IEEE: Copy

S. Yousefi Saqqezi, A. AZAMIAN JAZI, R. HEMMATI, and N. JIVAD, “Effects of Combined Exercise (aerobic + resistance) on the Expression of miR-301a and some Indicators of Motor Function in Women with Multiple Sclerosis (MS),” JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, vol. 9, no. 2 , pp. 1474–1486, 2019, [Online]. Available: https://sid.ir/paper/361962/en

Related Journal Papers