Effects of Resistance Training and HMB Supplementation on Responses of hs-CRP and Lipid Profiles to Strenuous Activity in Adult Male Rats

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AGHAEI F.; SHADMEHRI S.; SOLEYMANI A.A.

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Journal: JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY Year:2019 | Volume:14 | Issue:3 Page(s): 31-40

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Title

Effects of Resistance Training and HMB Supplementation on Responses of hs-CRP and Lipid Profiles to Strenuous Activity in Adult Male Rats

Author(s)

AGHAEI F. | SHADMEHRI S. | SOLEYMANI A.A. | Issue Writer Certificate

Keywords

Supplements HMBQ1

Eccentric resistance trainingQ2

hs-CRPQ1

Lipid profileQ1

Abstract

Background and Objectives: Various types of exercise cause damages at cellular levels in muscles. Muscle damages caused by exercise increase levels of C-reactive protein (CRP) in blood. The aim of this study was to assess effects of resistance training and ta-hydroxy beta-methylbutyric acid (HMB) supplementation on responses of high sensitivity Creactive protein (hs-CRP) and Lipid profiles to strenuous activity in adult male rats. Materials & Methods: In total, 32 healthy rat were randomly divided into four major groups of training, supplement, training-supplement and control groups. The experimental group carried out eccentric resistance for two weeks, five days a week. Supplementary groups received supplemental HMB daily for up to 450 mg/kg body weight per day using gavage. In general, one session of strenuous eccentric resistance activity (stepping down from ladder with a gradient of 80% by closing 120% 1RM at the back of the rat tails) was carried out 24 h before and after the intervention (supplementary and training). Data analysis was carried out using ANOVA and Tukey post hoc test at P ≤ 0. 05. Results: Results showed that HMB supplementation and Eccentric resistance training alone included no effects on hs-CRP, cholesterol, triglycerides, LDL-C and HDL-C in adult male rats after strenuous activity (P < 0. 05). However, combination of HMB supplementation and Eccentric resistance training included a significant effect on these variables after a strenuous activity in adult male rats (P= 0. 001). Conclusion: Based on the results, combination of supplemental HMB and Eccentric resistance training may help improve inflammatory statuses and Lipid profiles.

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APA: Copy

AGHAEI, F., SHADMEHRI, S., & SOLEYMANI, A.A.. (2019). Effects of Resistance Training and HMB Supplementation on Responses of hs-CRP and Lipid Profiles to Strenuous Activity in Adult Male Rats. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY, 14(3 ), 31-40. SID. https://sid.ir/paper/361992/en

Vancouver: Copy

AGHAEI F., SHADMEHRI S., SOLEYMANI A.A.. Effects of Resistance Training and HMB Supplementation on Responses of hs-CRP and Lipid Profiles to Strenuous Activity in Adult Male Rats. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY[Internet]. 2019;14(3 ):31-40. Available from: https://sid.ir/paper/361992/en

IEEE: Copy

F. AGHAEI, S. SHADMEHRI, and A.A. SOLEYMANI, “Effects of Resistance Training and HMB Supplementation on Responses of hs-CRP and Lipid Profiles to Strenuous Activity in Adult Male Rats,” JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY, vol. 14, no. 3 , pp. 31–40, 2019, [Online]. Available: https://sid.ir/paper/361992/en

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