The effect of aqua-ethanolic extract of yellow horned poppy (Glaucium flavum Crantz) on serum activity of hepatic enzymes and insulin concentration in diabetic male rats induced by alloxan

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Khoshvaghti Ameneh; Darya Gholam Hossein; Bikarannejad Pouria; Zarghami Fatemeh

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Feyz Medical Sciences Journal Year:2019 | Volume:23 | Issue:2 Page(s): 117-124

Download Full-Text

Persian Verion

View:

506

Download:

Cites:

Information Journal Paper

Title

The effect of aqua-ethanolic extract of yellow horned poppy (Glaucium flavum Crantz) on serum activity of hepatic enzymes and insulin concentration in diabetic male rats induced by alloxan

Author(s)

Khoshvaghti Ameneh | Darya Gholam Hossein | Bikarannejad Pouria | Zarghami Fatemeh | Issue Writer Certificate

Keywords

Diabetes mellitusQ2

Glaucium flavum CrantzQ1

Liver functional enzymesQ2

InsulinQ1

RatQ2

AlloxanQ2

Abstract

Background: Glaucium flavum Crantz (Yellow Horned Poppy, YPH) is used to reduce complications of diabetes in Iranian folk medicine. This study was conducted to compare the effect of aqua-ethanolic extract of Yellow Horned Poppy and Glibenclamide on serum levels of AST, ALT, ALP and Insulin in diabetic Rats induced by Alloxan. Materials and Methods: In this experimental study, 40 adult male Wistar Rats were randomly divided into five groups of eight: healthy control, healthy treated with 500mg/kg body weight (BW) of the YPH extract (healthy+YPH), diabetic control, diabetic treated with 500mg/kg BW of the extract (diabetic+YPH), diabetic treated with 5μ g/kg BW of Glibenclamide (diabetic+ medicine). Diabetes was induced by injection of Alloxan. After a month, blood samples were collected and serum levels of liver enzymes and Insulin were also measured. Finally, the data were analyzed by one-way ANOVA and Tukey's post-hoc test. Results: The activity of AST and ALP enzymes in the diabetic+YPH group was significantly higher than that in the diabetic+drug group (P=0. 04). Also, ALT activity and Insulin concentRation in diabetic+YPH group significantly increased compared to diabetic control group (P<0. 001). Conclusion: The findings of this study reveal that oral administRation of the YHP extract in addition to its hepatoprotective activity against diabetes-induced stress, can enhance serum Insulin level.

Cites

No record.

References

Cite

APA: Copy

Khoshvaghti, Ameneh, Darya, Gholam Hossein, Bikarannejad, Pouria, & Zarghami, Fatemeh. (2019). The effect of aqua-ethanolic extract of yellow horned poppy (Glaucium flavum Crantz) on serum activity of hepatic enzymes and insulin concentration in diabetic male rats induced by alloxan. FEYZ, 23(2 ), 117-124. SID. https://sid.ir/paper/362232/en

Vancouver: Copy

Khoshvaghti Ameneh, Darya Gholam Hossein, Bikarannejad Pouria, Zarghami Fatemeh. The effect of aqua-ethanolic extract of yellow horned poppy (Glaucium flavum Crantz) on serum activity of hepatic enzymes and insulin concentration in diabetic male rats induced by alloxan. FEYZ[Internet]. 2019;23(2 ):117-124. Available from: https://sid.ir/paper/362232/en

IEEE: Copy

Ameneh Khoshvaghti, Gholam Hossein Darya, Pouria Bikarannejad, and Fatemeh Zarghami, “The effect of aqua-ethanolic extract of yellow horned poppy (Glaucium flavum Crantz) on serum activity of hepatic enzymes and insulin concentration in diabetic male rats induced by alloxan,” FEYZ, vol. 23, no. 2 , pp. 117–124, 2019, [Online]. Available: https://sid.ir/paper/362232/en

Related Journal Papers