THE EFFECT OF ORAL ADMINISTRATION OF ARTEMISIA DRACUNCULUS ON BLOOD GLUCOSE AND LIPID PROFILE IN MALE DIABETIC RATS

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ROUGHANI M.; BALUCHNEJADMOJARAD TOURANDOKHT; ROUGHANI DEHKORDI F.

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Journal: Iranian Journal of Endocrinology & Metabolism Year:2004 | Volume:6 | Issue:3(SN 23) Page(s): 0-0

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Title

THE EFFECT OF ORAL ADMINISTRATION OF ARTEMISIA DRACUNCULUS ON BLOOD GLUCOSE AND LIPID PROFILE IN MALE DIABETIC RATS

Author(s)

ROUGHANI M. | BALUCHNEJADMOJARAD TOURANDOKHT | ROUGHANI DEHKORDI F. | Issue Writer Certificate

Keywords

ARTEMISIA DRACUNCULUSQ2

DIABETES MELLITUSQ3

GLUCOSEQ3

TRIGLYCERIDEQ3

CHOLESTEROLQ3

RATQ2

Abstract

Introduction: There have been some reports documenting the antidiabetic effect of tarragon in traditional medicine. In this investigation we studied the hypoglycemic and hypolipidemic effects of tarragon in an experimental model of insulin-dependent DIABETES MELLITUS. Materials and Methods: Male Wistar RATs (n=32) were divided into four groups, i.e. the control, tarragon-treated, diabetic, and diabetic tarragon-treated groups. For induction of diabetes, streptozotocin (STZ; 60 mg/Kg; i. p. ) was used at a single dose. A serum GLUCOSE level higher than 250 mg/dL was considered a diabetic state. The treatment groups received oral administration of tarragon-mixed pelleted food (6. 25%) for a period of one month. Results: Statistical analysis and comparison of data obtained one week prior to and two weeks after administration of tarragon showed increase in serum GLUCOSE levels among the diabetic group (p<0.001); tarragon treatment produced no significant reduction in this respect. In addition, the TRIGLYCERIDE level was higher in the diabetic group and there was a significant reduction in this parameter in the tarragon-treated diabetic group as compared to the untreated diabetic group in the fourth week after the experiment (p<0. 01). CHOLESTEROL levels, however, showed no significant reduction in the tarragon-treated diabetic group in comparison to the untreated diabetic group. Conclusion: The results of this study clearly indicate that oral administration of tarragon for one month could significantly reduce only serum TRIGLYCERIDE levels in insulin-dependent diabetic RATs.

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APA: Copy

ROUGHANI, M., BALUCHNEJADMOJARAD, TOURANDOKHT, & ROUGHANI DEHKORDI, F.. (2004). THE EFFECT OF ORAL ADMINISTRATION OF ARTEMISIA DRACUNCULUS ON BLOOD GLUCOSE AND LIPID PROFILE IN MALE DIABETIC RATS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 6(3(SN 23)), 0-0. SID. https://sid.ir/paper/362267/en

Vancouver: Copy

ROUGHANI M., BALUCHNEJADMOJARAD TOURANDOKHT, ROUGHANI DEHKORDI F.. THE EFFECT OF ORAL ADMINISTRATION OF ARTEMISIA DRACUNCULUS ON BLOOD GLUCOSE AND LIPID PROFILE IN MALE DIABETIC RATS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2004;6(3(SN 23)):0-0. Available from: https://sid.ir/paper/362267/en

IEEE: Copy

M. ROUGHANI, TOURANDOKHT BALUCHNEJADMOJARAD, and F. ROUGHANI DEHKORDI, “THE EFFECT OF ORAL ADMINISTRATION OF ARTEMISIA DRACUNCULUS ON BLOOD GLUCOSE AND LIPID PROFILE IN MALE DIABETIC RATS,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 6, no. 3(SN 23), pp. 0–0, 2004, [Online]. Available: https://sid.ir/paper/362267/en

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