THE EFFECT ALLIUM AMPELOPRASUM FEEDING ON SERUM LEVEL OF GLUCOSE, TRIGLYCERIDE, AND TOTAL CHOLESTEROL OF DIABETIC RATS

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ROUGHANI M.; AGHAEI MAHBOUBEH

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Journal: Koomesh Year:2007 | Volume:8 | Issue:2 Page(s): 73-77

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Title

THE EFFECT ALLIUM AMPELOPRASUM FEEDING ON SERUM LEVEL OF GLUCOSE, TRIGLYCERIDE, AND TOTAL CHOLESTEROL OF DIABETIC RATS

Author(s)

ROUGHANI M. | AGHAEI MAHBOUBEH | Issue Writer Certificate

Keywords

ALLIUM AMPELOPRASUMQ3

GLUCOSEQ2

LIPIDQ3

DIABETES MELLITUSQ3

CHRONIC ADMINISTRATIONQ3

RATQ2

Abstract

Introduction: Use of medicinal plants for attenuation of hyperglycemia and restoration of LIPIDs to normal level is clinically important. Since garlic and leek are similar regarding some effective substances as well as the antidiabetic effect of garlic, this study was performed to evaluate the effect of chronic oral administration of leek (ALLIUM AMPELOPRASUM) on serum level of GLUCOSE, triglyceride, and total cholesterol of diabetic RATs.Materials and Methods: In the current study, 36 male Wistar RATs were randomly divided into 4 groups, i.e. control, AA-treated control, diabetic, and AA-treated diabetic group. The treatment groups received oral administration of plant-mixed pelleted food (6.25%) for 4 weeks. Serum GLUCOSE, triglyceride, and total cholesterol levels were measured in all animals prior to the treatment as well as two and four weeks after the treatment.Results: Serum GLUCOSE levels were increased 4 weeks after the treatment in diabetic group compared to those levels was observed one week before the treatment (P<0.0001) and also AA treatment of diabetic RATs did exert a significant hypoglycemic effect as compared to untreated diabetics (p<0.05). In addition, triglyceride levels were increased 4 weeks after the treatment in the diabetic group in comparison with related levels observed one week prior to the treatment (P<0.05) and there was a significant lower level of triglyceride in AA-treated diabetic RATs (p<0.05). Furthermore, a similar significant reduction was obtained for treated-diabetic group as compared to diabetic group regarding serum cholesterol level (p<0.01).Conclusion: Oral CHRONIC ADMINISTRATION of AA could reduce serum GLUCOSE, triglyceride, and cholesterol levels of STZ-diabetic RATs.

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APA: Copy

ROUGHANI, M., & AGHAEI, MAHBOUBEH. (2007). THE EFFECT ALLIUM AMPELOPRASUM FEEDING ON SERUM LEVEL OF GLUCOSE, TRIGLYCERIDE, AND TOTAL CHOLESTEROL OF DIABETIC RATS. KOOMESH, 8(2), 73-77. SID. https://sid.ir/paper/37166/en

Vancouver: Copy

ROUGHANI M., AGHAEI MAHBOUBEH. THE EFFECT ALLIUM AMPELOPRASUM FEEDING ON SERUM LEVEL OF GLUCOSE, TRIGLYCERIDE, AND TOTAL CHOLESTEROL OF DIABETIC RATS. KOOMESH[Internet]. 2007;8(2):73-77. Available from: https://sid.ir/paper/37166/en

IEEE: Copy

M. ROUGHANI, and MAHBOUBEH AGHAEI, “THE EFFECT ALLIUM AMPELOPRASUM FEEDING ON SERUM LEVEL OF GLUCOSE, TRIGLYCERIDE, AND TOTAL CHOLESTEROL OF DIABETIC RATS,” KOOMESH, vol. 8, no. 2, pp. 73–77, 2007, [Online]. Available: https://sid.ir/paper/37166/en

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