EVALUATION OF THE EFFECTS OF ADMINISTRATION OF MICRODOSE GNRH-A COMBINATION WITH GONADOTROPINS ON THE STIMULATION OF OVARIES IN ART CYCLES OF POOR RESPONDER PATIENTS

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DAVAR R.; AFLATOUNIAN A.

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Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2004 | Volume:11 | Issue:4 Page(s): 63-69

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Title

EVALUATION OF THE EFFECTS OF ADMINISTRATION OF MICRODOSE GNRH-A COMBINATION WITH GONADOTROPINS ON THE STIMULATION OF OVARIES IN ART CYCLES OF POOR RESPONDER PATIENTS

Author(s)

DAVAR R. | AFLATOUNIAN A. | Issue Writer Certificate

Keywords

MICRODOSEGNRH- AQ4

ARTQ4

POOR RESPONDERQ3

Abstract

Introduction: GnRH-a+HMG combination is used for controlled ovarian hyperstimulation in IVF cycles. GnRH-a can be used in 2 ways;1) in follicular phase or 2) in luteal phase. There is discrepancy about its effect when used in the follicular phase. In this study, we determined the effects of microdose GnRH-a in Poor-responder patients. Materials & Methods: 61 poor-responders who were candidates for IVF or microinjection used low dose oral contraceptive pills for 21 days and then Bouserelin 40 µg subcutaneously 2 times /day from 3rd day of cycle and HMG 3Amp/day from 5th day of cycle. Datas were analyzed by SPSS chi –Square and Fisher Exact test. Results: Number of follicles, oocytes, embryo and pregnancy rate were determined, and compared with previous cycles. Difference was significant in all cases. (P < 0.05). Pregnancies occurred in 3 patients (5%). Conclusion: Results of this study showed that use of microdose GnRH-a +HMG for controlled ovarian hyperstimulation in IVF cycles can lead to formation of follicles, oocytes and embryoes in POOR RESPONDERs.

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APA: Copy

DAVAR, R., & AFLATOUNIAN, A.. (2004). EVALUATION OF THE EFFECTS OF ADMINISTRATION OF MICRODOSE GNRH-A COMBINATION WITH GONADOTROPINS ON THE STIMULATION OF OVARIES IN ART CYCLES OF POOR RESPONDER PATIENTS. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 11(4), 63-69. SID. https://sid.ir/paper/36267/en

Vancouver: Copy

DAVAR R., AFLATOUNIAN A.. EVALUATION OF THE EFFECTS OF ADMINISTRATION OF MICRODOSE GNRH-A COMBINATION WITH GONADOTROPINS ON THE STIMULATION OF OVARIES IN ART CYCLES OF POOR RESPONDER PATIENTS. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2004;11(4):63-69. Available from: https://sid.ir/paper/36267/en

IEEE: Copy

R. DAVAR, and A. AFLATOUNIAN, “EVALUATION OF THE EFFECTS OF ADMINISTRATION OF MICRODOSE GNRH-A COMBINATION WITH GONADOTROPINS ON THE STIMULATION OF OVARIES IN ART CYCLES OF POOR RESPONDER PATIENTS,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 11, no. 4, pp. 63–69, 2004, [Online]. Available: https://sid.ir/paper/36267/en

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