EFFECT OF CONSUMPTION OF TRIBULUS TERRESTRIS ON SERUM GLUCOSE AND LIPID LEVELS IN DIABETIC RATS

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ROGHANI M.; BALUCHNEJADMOJARAD TOURANDOKHT; ANDALIBI N.; ANSARI F.; SHARAYELI M.

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Journal: Journal of Shahid Sadoughi University of Medical Sciences Year:2010 | Volume:18 | Issue:1 (69) Page(s): 17-23

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Title

EFFECT OF CONSUMPTION OF TRIBULUS TERRESTRIS ON SERUM GLUCOSE AND LIPID LEVELS IN DIABETIC RATS

Author(s)

Keywords

TRIBULUS TERRESTRISQ2

DIABETES MELLITUSQ3

GLUCOSEQ2

LIPIDSQ3

Abstract

Introduction: The effect of TRIBULUS TERRESTRIS (TT) on serum GLUCOSE and lipid levels was investigated in an experimental model of DIABETES MELLITUS in rats. Methods: Female Wistar rats were divided into control, TT-treated control, diabetic, glibenclamide-treated, and TT-treated diabetic groups. For induction of diabetes, streptozotcin (STZ) was administered (60 mg/Kg). Meanwhile, TT-treated groups received TT mixed with standard pelleted food at a weight ratio of 6.25% for 6 weeks. Serum GLUCOSE and lipid levels were determined before the study and at the 3rd and 4th week after the study. Results: Serum GLUCOSE was significantly lower in TT-treated diabetic rats at 3rd and 6th weeks as compared to untreated diabetics (p<0.01 and p<0.005, respectively). In addition, serum total cholesterol, triglyceride, and LDL-cholesterol showed a significant reduction in TT-treated diabetic rats as compared to untreated diabetics (p<0.05). On the other hand, HDL-cholesterol level did not change significantly in TT-treated diabetic group as compared to untreated diabetic group. Conclusions: Oral administration of TT has a significant hypoglycemic effect and in long term leads to appropriate changes in serum LDL-cholesterol, total cholesterol, and triglyceride levels, but does not affect HDL-cholesterol levels in diabetic rats.

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APA: Copy

ROGHANI, M., BALUCHNEJADMOJARAD, TOURANDOKHT, ANDALIBI, N., ANSARI, F., & SHARAYELI, M.. (2010). EFFECT OF CONSUMPTION OF TRIBULUS TERRESTRIS ON SERUM GLUCOSE AND LIPID LEVELS IN DIABETIC RATS. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 18(1 (69)), 17-23. SID. https://sid.ir/paper/36378/en

Vancouver: Copy

ROGHANI M., BALUCHNEJADMOJARAD TOURANDOKHT, ANDALIBI N., ANSARI F., SHARAYELI M.. EFFECT OF CONSUMPTION OF TRIBULUS TERRESTRIS ON SERUM GLUCOSE AND LIPID LEVELS IN DIABETIC RATS. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2010;18(1 (69)):17-23. Available from: https://sid.ir/paper/36378/en

IEEE: Copy

M. ROGHANI, TOURANDOKHT BALUCHNEJADMOJARAD, N. ANDALIBI, F. ANSARI, and M. SHARAYELI, “EFFECT OF CONSUMPTION OF TRIBULUS TERRESTRIS ON SERUM GLUCOSE AND LIPID LEVELS IN DIABETIC RATS,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 18, no. 1 (69), pp. 17–23, 2010, [Online]. Available: https://sid.ir/paper/36378/en

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