Comparison of cartilage specific gene expression between condrcoyets treated with adipose derived stem cells supernatant and chondrocytes co-cultured with stem cells

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MONTASERI AZADEH; Zeynali Maryam; Hatami Seyyedeh Mahdiyeh; Hassan Famian Maryam

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2019 | Volume:41 | Issue:2 Page(s): 97-105

Download Full-Text

Persian Verion

View:

331

Download:

Cites:

Information Journal Paper

Title

Comparison of cartilage specific gene expression between condrcoyets treated with adipose derived stem cells supernatant and chondrocytes co-cultured with stem cells

Author(s)

MONTASERI AZADEH | Zeynali Maryam | Hatami Seyyedeh Mahdiyeh | Hassan Famian Maryam | Issue Writer Certificate

Keywords

ChondrocyteQ1

CartilageQ2

Stem CellsQ2

Adipose TissueQ2

GeneQ2

Abstract

Background: It has been accepted that different effects of Stem Cells can be contributed to their paracrine secretions into the supernatant. Accordingly, the goal of this study is to evaluate the probable effects of adipose derived Stem Cells (ASCs) supernatant on Chondrocyte Gene expression and to compare it with co-culture condition of Chondrocyte and ASCs. Methods: To evaluate the supernatant effects, Chondrocyte at the second passage were treated with ASCs-supernatant for 72 hr. Co-culture of cells were performed by seeding the same number of Chondrocytes and ASCs in culture flasks for 72 hr too. After this period, cells in both groups were prepared for evaluation of Cartilage specific Genes expression using Real time RT-PCR technique. Data were analyzed using Two-Way ANOVA and Tukey's post-test. Results: Treatment of Chondrocytes with ASCs supernatant resulted in significant increase in the expression of Collagen II and Sox-9, but that of the aggrecan and COMP did not change significantly. Conclusion: ASCs supernatant can be a beneficial medium compared to the Stem Cells itself and can be introduced as a candidate for promotion of Cartilage lesions healing.

Cites

No record.

References

No record.

Cite

APA: Copy

MONTASERI, AZADEH, Zeynali, Maryam, Hatami, Seyyedeh Mahdiyeh, & Hassan Famian, Maryam. (2019). Comparison of cartilage specific gene expression between condrcoyets treated with adipose derived stem cells supernatant and chondrocytes co-cultured with stem cells. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 41(2 ), 97-105. SID. https://sid.ir/paper/364657/en

Vancouver: Copy

MONTASERI AZADEH, Zeynali Maryam, Hatami Seyyedeh Mahdiyeh, Hassan Famian Maryam. Comparison of cartilage specific gene expression between condrcoyets treated with adipose derived stem cells supernatant and chondrocytes co-cultured with stem cells. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;41(2 ):97-105. Available from: https://sid.ir/paper/364657/en

IEEE: Copy

AZADEH MONTASERI, Maryam Zeynali, Seyyedeh Mahdiyeh Hatami, and Maryam Hassan Famian, “Comparison of cartilage specific gene expression between condrcoyets treated with adipose derived stem cells supernatant and chondrocytes co-cultured with stem cells,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 41, no. 2 , pp. 97–105, 2019, [Online]. Available: https://sid.ir/paper/364657/en

Related Journal Papers