The effect of eight weeks combined exercise training on the levels of adropin and VEGFR-2 in obese men with hypertension

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Roshdi bonab Reza; EBRAHIM KHOSRO; GHAZALIAN FARSHAD; Afrasiabi Rad Abbas

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Journal: Razi Journal of Medical Sciences Year:2019 | Volume:26 | Issue:8 Page(s): 78-88

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Title

The effect of eight weeks combined exercise training on the levels of adropin and VEGFR-2 in obese men with hypertension

Author(s)

Roshdi bonab Reza | EBRAHIM KHOSRO | GHAZALIAN FARSHAD | Afrasiabi Rad Abbas | Issue Writer Certificate

Keywords

HypertensionQ1

Combined trainingQ1

AdropinQ1

VEGFR-2Q1

Abstract

Background: Hypertension is one of the main risk factors for cardiovascular disease that is mostly associated with obesity and physical inactivity. The aim of present study was to identify the effect of eight weeks combined exercise training on the levels of Adropin and VEGFR-2 in obese men with Hypertension. Methods: The study was semi-experimental. 24 obese men with Hypertension (systolic blood pressure more than 140 or diastolic blood pressure more than 90 mmHg) were assigned into two controls and Combined training groups. Combined training program was conducted for eight weeks with three sessions per week. In each Combined training session, initially circuit resistance training was performed which was then immediately followed by endurance training. 48 hours after last exercise session, blood samples were collected and Adropin and VEGFR-2 levels were measured by ELISA method. Data were analyzed by SPSS software version 24 and analysis of covariance test. Results: The results showed that Adropin (p=0. 041) and VEGFR-2 (p>0. 001) significantly increased in combined exercise training group as compared to control group. Decrease in systolic blood pressure (p>0. 001) and lipid profile improvement (p<0. 05) were also significant in Combined training group in comparison to control group. Conclusion: Although the information is limited about the effects of combined exercise training on Hypertension, the present study results indicated that Combined training had positive effects in controlling blood pressure in hypertensive patients which is partly related to up regulation of Adropin and VEGFR-2 levels.

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APA: Copy

Roshdi bonab, Reza, EBRAHIM, KHOSRO, GHAZALIAN, FARSHAD, & Afrasiabi Rad, Abbas. (2019). The effect of eight weeks combined exercise training on the levels of adropin and VEGFR-2 in obese men with hypertension. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 26(8 ), 78-88. SID. https://sid.ir/paper/364664/en

Vancouver: Copy

Roshdi bonab Reza, EBRAHIM KHOSRO, GHAZALIAN FARSHAD, Afrasiabi Rad Abbas. The effect of eight weeks combined exercise training on the levels of adropin and VEGFR-2 in obese men with hypertension. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2019;26(8 ):78-88. Available from: https://sid.ir/paper/364664/en

IEEE: Copy

Reza Roshdi bonab, KHOSRO EBRAHIM, FARSHAD GHAZALIAN, and Abbas Afrasiabi Rad, “The effect of eight weeks combined exercise training on the levels of adropin and VEGFR-2 in obese men with hypertension,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 26, no. 8 , pp. 78–88, 2019, [Online]. Available: https://sid.ir/paper/364664/en

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