An in vitro Evaluation of Antifungal Effectiveness of Alum on the Growth of Candida Albicans and Candida Tropicalis Growth

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MALEKZADEH HOSEIN; AMIN MANSOUR; Babadi fateme; Soweyti Fateme

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Journal: Jundishapur Scientific Medical Journal Year:2019 | Volume:18 | Issue:4 Page(s): 403-414

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Title

An in vitro Evaluation of Antifungal Effectiveness of Alum on the Growth of Candida Albicans and Candida Tropicalis Growth

Author(s)

MALEKZADEH HOSEIN | AMIN MANSOUR | Babadi fateme | Soweyti Fateme | Issue Writer Certificate

Keywords

White AlumQ3

AlumQ2

Candida AlbicansQ1

Candida TherapyQ1

Infection ControlQ2

DentistryQ2

Abstract

Background and Objective: Candida Albicans and Candida tropicalis are the most common etiologic factors in the diseases caused by yeast species. Considering the increased resistance of fungi to some antifungal drugs and many of these drugs are toxic and expensive; studies specifically designed to assess the antifungal effectiveness of natural products are necessary. Therefore, the aim of this study was to investigate the effect of Alum/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">White Alum (Alum) on the prevention of Candida Albicans and Candida tropicalis under in vitro setting. Materials and Methods: In this laboratory study, using modified E. test method, Alum/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">White Alum solutions were prepared at concentrations of (8, 4, 2, 1, 0. 5, 0. 25 and 0. 125 mg/100ml) then10 μ Lof each dilution Poured in blank disks that placed linearly on the culture medium inoculated with the fungus, then for 24 hours due to the low growth rate of these fungi, the petri was incubated at 37 ° C, and the minimum growth inhibitory concentration (MIC) was obtained. It should be noted that the test was repeated three times and averaged. Results: The findings of this study showed that Alum/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">White Alum has a positive effect on inhibiting the growth of Candida Albicans and Candida tropicalis colonies. MIC for Candida Albicans and Candida capillaries was 0. 13 and 0. 06 mg / ml, respectively. Conclusion: According to the results of this study, the use of Alum/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank">White Alum can be a good cure in the treatment of Candida Albicans and Candida tropicalis infection in dental treatment.

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APA: Copy

MALEKZADEH, HOSEIN, AMIN, MANSOUR, Babadi, fateme, & Soweyti, Fateme. (2019). An in vitro Evaluation of Antifungal Effectiveness of Alum on the Growth of Candida Albicans and Candida Tropicalis Growth. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, 18(4 ), 403-414. SID. https://sid.ir/paper/365405/en

Vancouver: Copy

MALEKZADEH HOSEIN, AMIN MANSOUR, Babadi fateme, Soweyti Fateme. An in vitro Evaluation of Antifungal Effectiveness of Alum on the Growth of Candida Albicans and Candida Tropicalis Growth. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL[Internet]. 2019;18(4 ):403-414. Available from: https://sid.ir/paper/365405/en

IEEE: Copy

HOSEIN MALEKZADEH, MANSOUR AMIN, fateme Babadi, and Fateme Soweyti, “An in vitro Evaluation of Antifungal Effectiveness of Alum on the Growth of Candida Albicans and Candida Tropicalis Growth,” JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, vol. 18, no. 4 , pp. 403–414, 2019, [Online]. Available: https://sid.ir/paper/365405/en

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