Histomorphometrical Study of the Effect of Platelet-rich Plasma Therapy on the Damage Caused by the Torsion-Detorsion Testicular in Mice

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Aghaei borashan F.; SHAHROOZ RASOUL; AHMADI A.; Mazaheri Khamene R.; IMANI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ADVANCED BIOMEDICAL SCIENCES Year:2018 | Volume:8 | Issue:3 Page(s): 818-889

Download Full-Text

Persian Verion

View:

689

Download:

Cites:

Information Journal Paper

Title

Histomorphometrical Study of the Effect of Platelet-rich Plasma Therapy on the Damage Caused by the Torsion-Detorsion Testicular in Mice

Author(s)

Keywords

Testicular Torsion-DetorsionQ1

Platelet Rich PlasmaQ1

HistomorphometryQ2

TestisQ2

MiceQ1

Abstract

Background & Objectives: Testicular Torsion is one of the emergency cases which is caused by twisting of the spermatic cord; Detorsion leads to the recirculation of blood and ultimately, more damage occurs in Testis. Platelet-Rich plasma (PRP) contains several growth factors and cytokines that can restore tissue and rebuild cells, so in this study, PRP was used to evaluate its effects. Materials & Methods: Twenty-eight adult male Mice were randomly divided into three equal groups (n = 6). The first group, is the healthy control, without testicular twisting. Group II: Torsion Detorsion (TD) + PBS (phosphate-buffer-solution) group, Group III: The TD + PRP group. In these two groups spermatic cord were twisted for one hour, and after detorsion, PBS and PRP were injected into the rete Testis, respectively. 35 days after surgery, left Testis was sampled for histomorphometrical examinations. Obtained data were statistically compared by ANOVA and post hoc-Tukey test (P <0. 05). Results: Obtained data from the mean thickness of germinal epithelium, diameter of seminiferous tubules (P<0. 01), and, the spermatogenesis indices (P<0. 001) were decreased significantly in TD+ PBS group. The thickness of the Testis capsule and the lumen of seminiferous tubules showed a significant increase (P<0. 01). While, PRP significantly improved these parameters (P<0. 01). Conclusion: Testicular TD causes many impacts and disorganization in the male reproductive system, and resulting infertility. It seems that, PRP due to possession ample of growth factors, able to relatively improve the undesirable effects of TD.

Cites

No record.

References

No record.

Cite

APA: Copy

Aghaei borashan, F., SHAHROOZ, RASOUL, AHMADI, A., Mazaheri Khamene, R., & IMANI, M.. (2018). Histomorphometrical Study of the Effect of Platelet-rich Plasma Therapy on the Damage Caused by the Torsion-Detorsion Testicular in Mice. JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, 8(3 ), 818-889. SID. https://sid.ir/paper/365537/en

Vancouver: Copy

Aghaei borashan F., SHAHROOZ RASOUL, AHMADI A., Mazaheri Khamene R., IMANI M.. Histomorphometrical Study of the Effect of Platelet-rich Plasma Therapy on the Damage Caused by the Torsion-Detorsion Testicular in Mice. JOURNAL OF ADVANCED BIOMEDICAL SCIENCES[Internet]. 2018;8(3 ):818-889. Available from: https://sid.ir/paper/365537/en

IEEE: Copy

F. Aghaei borashan, RASOUL SHAHROOZ, A. AHMADI, R. Mazaheri Khamene, and M. IMANI, “Histomorphometrical Study of the Effect of Platelet-rich Plasma Therapy on the Damage Caused by the Torsion-Detorsion Testicular in Mice,” JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, vol. 8, no. 3 , pp. 818–889, 2018, [Online]. Available: https://sid.ir/paper/365537/en

Related Journal Papers