EFFECT OF VITAMIN D SUPPLEMENTATION ON SYMPTOMS AND C-REACTIVE PROTEIN AMONG PATIENTS WITH MIGRAINE

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MOTTAGHI TAYEBEH; ASKARI GHOLAMREZA; KHORVASH FARIBORZ; MARACY MOHAMMAD REZA; GHIASVAND REZA

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Journal: Koomesh Year:2015 | Volume:16 | Issue:2 (54) Page(s): 207-212

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Title

EFFECT OF VITAMIN D SUPPLEMENTATION ON SYMPTOMS AND C-REACTIVE PROTEIN AMONG PATIENTS WITH MIGRAINE

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Keywords

VITAMIN DQ2

MIGRAINE DISORDERSQ2

C-REACTIVE PROTEINQ1

Abstract

Introduction: Migraine is the most common form of headache around the world including Iran. In recent years, particular notice has been made to the relationship between VITAMIN D and migraine. Therefore, the purpose of the current study is to investigate the relationship between serum VITAMIN D levels and CRP and migraine symptoms in patients.Materials and Methods: This study was carried out as a randomized, double-blind clinical trial. Patients were randomly assigned for either intervention or control groups. Patients consumed a VITAMIN D supplement or placebo (50000 IU/ week) during 10 weeks. Before and after the intervention, serum levels of VITAMIN D and CRP were measured and migraine symptoms were assessed. To assess the effect of VITAMIN D supplements on migraine symptoms including severity, duration, frequency of headache attacks and headache diary result (HDR), multivariate and uni-variate analysis of covarients were used as statistical methods of analysis.Results: Significant differences were observed in mean headache frequency and diary result (HDR) between the two groups (P=0.06 and P=0.04). However, the difference in mean migraine frequencies between the groups displayed a significance threshold (P=0.06). The relationship between migraine headaches and C - reactive protein (CRP) was not determined.Conclusion: the outcome of this study suggests that VITAMIN D supplements are effective in reducing migraine symptoms including frequency of headache attacks and headache diary result in patients.

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APA: Copy

MOTTAGHI, TAYEBEH, ASKARI, GHOLAMREZA, KHORVASH, FARIBORZ, MARACY, MOHAMMAD REZA, & GHIASVAND, REZA. (2015). EFFECT OF VITAMIN D SUPPLEMENTATION ON SYMPTOMS AND C-REACTIVE PROTEIN AMONG PATIENTS WITH MIGRAINE. KOOMESH, 16(2 (54)), 207-212. SID. https://sid.ir/paper/37150/en

Vancouver: Copy

MOTTAGHI TAYEBEH, ASKARI GHOLAMREZA, KHORVASH FARIBORZ, MARACY MOHAMMAD REZA, GHIASVAND REZA. EFFECT OF VITAMIN D SUPPLEMENTATION ON SYMPTOMS AND C-REACTIVE PROTEIN AMONG PATIENTS WITH MIGRAINE. KOOMESH[Internet]. 2015;16(2 (54)):207-212. Available from: https://sid.ir/paper/37150/en

IEEE: Copy

TAYEBEH MOTTAGHI, GHOLAMREZA ASKARI, FARIBORZ KHORVASH, MOHAMMAD REZA MARACY, and REZA GHIASVAND, “EFFECT OF VITAMIN D SUPPLEMENTATION ON SYMPTOMS AND C-REACTIVE PROTEIN AMONG PATIENTS WITH MIGRAINE,” KOOMESH, vol. 16, no. 2 (54), pp. 207–212, 2015, [Online]. Available: https://sid.ir/paper/37150/en

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