Effects of six-week high-intensity interval training (HIIT) on PGC-1α methylation in gastrocnemius muscle of obese rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Maleki Shabnam; NAZARALI PARVANEH; RAZAVI AMENEH; KAZEMI FAHIMEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download Full-Text

Persian Verion

View:

273

Download:

Cites:

Information Journal Paper

Title

Effects of six-week high-intensity interval training (HIIT) on PGC-1α methylation in gastrocnemius muscle of obese rats

Author(s)

Maleki Shabnam | NAZARALI PARVANEH | RAZAVI AMENEH | KAZEMI FAHIMEH | Issue Writer Certificate

Keywords

ObesityQ2

High fat dietQ1

PGC-1αmethylationQ1

High-intensity interval trainingQ1

Abstract

Backgrond: Obesity is associated with increased risk of many diseases. Methylation is an important factor in Obesity, indicating epigenetic changes. However, there is lack of data about PGC-1α methylation and regular exercise. The purpose of the present study was to determine effects of a six-week High-intensity interval training (HIIT) program on PGC-1α methylation in gastrocnemius muscle of obese male rats. Methods: In an experimental study, 24 male Wistar rats were randomly divided into four groups (six rats each): control healthy, trained healthy, control obese, and trained obese. Healthy group consumed normal diet and obese group consumed high-fat diet for six weeks. The trained healthy and trained obese performed swimming HIIT for six weeks. Then, 24 hours after the last session of training, gastrocnemius muscles of control and trained rats were extracted and then afterwards PGC-1α methylation was assayed. To analyze the data, paired sample t-test and one-way analysis of variance were used. Results: After six weeks, body weight of trained obese group, compared with control obese, decreased significantly (P=0. 021). In addition, after six-week HIIT, PGC-1α methylation of healthy (P=0. 010) and obese group (P=0. 037), compared with their control group, decreased significantly. Conclusion: It appears that six weeks of swimming HIIT can be effective on Obesity state and significantly reduce PGC-1α methylation in gastrocnemius muscle of obese male rats.

Cites

No record.

References

No record.

Cite

APA: Copy

Maleki, Shabnam, NAZARALI, PARVANEH, RAZAVI, AMENEH, & KAZEMI, FAHIMEH. (2019). Effects of six-week high-intensity interval training (HIIT) on PGC-1α methylation in gastrocnemius muscle of obese rats. PAJOUHESH DAR PEZESHKI, 42(4 ), 196-201. SID. https://sid.ir/paper/372407/en

Vancouver: Copy

Maleki Shabnam, NAZARALI PARVANEH, RAZAVI AMENEH, KAZEMI FAHIMEH. Effects of six-week high-intensity interval training (HIIT) on PGC-1α methylation in gastrocnemius muscle of obese rats. PAJOUHESH DAR PEZESHKI[Internet]. 2019;42(4 ):196-201. Available from: https://sid.ir/paper/372407/en

IEEE: Copy

Shabnam Maleki, PARVANEH NAZARALI, AMENEH RAZAVI, and FAHIMEH KAZEMI, “Effects of six-week high-intensity interval training (HIIT) on PGC-1α methylation in gastrocnemius muscle of obese rats,” PAJOUHESH DAR PEZESHKI, vol. 42, no. 4 , pp. 196–201, 2019, [Online]. Available: https://sid.ir/paper/372407/en

Related Journal Papers