The Effect of 6 Weeks Endurance Training on FSTL-1, NDNF, VEGF and Vascular Changes in Healthy Male Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

TOLOUEI AZAR J.; TOFIGHI A.; ARABZADEH E.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: SPORT PHYSIOLOGY (RESEARCH ON SPORT SCIENCE) Year:2019 | Volume:11 | Issue:41 Page(s): 169-186

Download Full-Text

Persian Verion

View:

554

Download:

Cites:

Information Journal Paper

Title

The Effect of 6 Weeks Endurance Training on FSTL-1, NDNF, VEGF and Vascular Changes in Healthy Male Rats

Author(s)

TOLOUEI AZAR J. | TOFIGHI A. | ARABZADEH E. | Issue Writer Certificate

Keywords

Endurance TrainingQ2

FSTL-1Q1

NDNFQ1

VEGFQ1

Male RatQ1

Abstract

In pathological conditions, FSTL-1, NDNF and VEGF proteins have a key regulatory role in function of the cardiovascular system. Relative to the role of these factors with exercise, research is limited. Therefore, the purpose of this study was to investigate the effect of 6 weeks of Endurance Training on FSTL-1, NDNF, VEGF and vascular changes in heart muscle of Male Rats. Methods: 10 male Wistar rats were randomly divided into 2 groups (n = 5): healthy control and exercise training. Endurance Training was performed for 6 weeks, 5 days a week, 30 minutes each session, and moderate intensity (65-55% VO2max). 48 hours after the last training session, the rats were anesthetized and their heart tissue removed. ELISA method was used to measure FSTL-1, NDNF and VEGF values and staining (H&E) was used to considering of vascular changes in heart tissue. Independent t-test and Pearson correlation test were used for data analysis (P <0. 05). Results: 6-week Endurance Training significantly increased the FSTL-1 values (P = 0. 002) and NDNF significantly decreased (P = 0. 001). The diameter of the vessels in the exercise training group decreased significantly (P = 0. 073). Conclusion: 6 weeks of Endurance Training increases the amount of FSTL-1 in the heart muscle, which it seems that very effective in preventing cardiovascular disease. Considering the results of VEGF and vascular histology, the physiological effects of NDNF on the induction of cardiac angiogenesis in healthy subjects with exercise training need further studies.

Cites

No record.

References

No record.

Cite

APA: Copy

TOLOUEI AZAR, J., TOFIGHI, A., & ARABZADEH, E.. (2019). The Effect of 6 Weeks Endurance Training on FSTL-1, NDNF, VEGF and Vascular Changes in Healthy Male Rats. SPORT PHYSIOLOGY (RESEARCH ON SPORT SCIENCE), 11(41 ), 169-186. SID. https://sid.ir/paper/377601/en

Vancouver: Copy

TOLOUEI AZAR J., TOFIGHI A., ARABZADEH E.. The Effect of 6 Weeks Endurance Training on FSTL-1, NDNF, VEGF and Vascular Changes in Healthy Male Rats. SPORT PHYSIOLOGY (RESEARCH ON SPORT SCIENCE)[Internet]. 2019;11(41 ):169-186. Available from: https://sid.ir/paper/377601/en

IEEE: Copy

J. TOLOUEI AZAR, A. TOFIGHI, and E. ARABZADEH, “The Effect of 6 Weeks Endurance Training on FSTL-1, NDNF, VEGF and Vascular Changes in Healthy Male Rats,” SPORT PHYSIOLOGY (RESEARCH ON SPORT SCIENCE), vol. 11, no. 41 , pp. 169–186, 2019, [Online]. Available: https://sid.ir/paper/377601/en

Related Journal Papers