THE RESPONSE OF SKELETAL MUSCLE SARCOMERIC PROTEINS TO 8 WEEK PROGRESSIVE RESISTANCE T RAINING IN SPRAGUE-DAWLEY RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GAEINI A.A.; KHALEDI N.; RAVASI A.A.; SAHEBGHADAM LOTFI A.; HEDAYATI M.; ARABKARI V.; SADR ALASHRAFI S.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: OLYMPIC Year:2012 | Volume:19 | Issue:4 (SERIAL 56) Page(s): 125-137

Download Full-Text

Persian Verion

View:

1,122

Download:

Cites:

Information Journal Paper

Title

THE RESPONSE OF SKELETAL MUSCLE SARCOMERIC PROTEINS TO 8 WEEK PROGRESSIVE RESISTANCE T RAINING IN SPRAGUE-DAWLEY RATS

Author(s)

Keywords

ALPHA-ACTININSQ2

FLEXOR HALLUCIS LONGUSQ2

RESISTANCE TRAININGQ2

VERTICAL LADDERQ2

Z-LINEQ2

Abstract

Alpha (a) -actinins are located in the skeletal muscle Z-LINE and form actin–ctin cross-links. It belongs to a highly conserved family of actin-binding proteins –the spectrin superfamily, which also contains the spectrins and dystrophin. Mammalian skeletal muscle has two isoforms: α-actinin-2 and a -actinin-3. However, the response of a-actinin to exercise training is little understood. Forty female Sprague-Dawley rats at the age of three months were obtained from Razi institute and assigned to a control (C; n=18) or exercise training (T; n=22) group. This study examined the effects of 8 weeks of RESISTANCE TRAINING on muscle mass and a -actinin-2 and a -actinin-3 levels in the FLEXOR HALLUCIS LONGUS muscle (FHL). The RESISTANCE TRAINING consisted of climbing (with 1-RM until exhaustion) a ladder carrying a load suspended from the tail. The weights were increased gradually throughout the 8 weeks of training. Following 8 weeks of training, we observed significant increase in absolute muscle mass in FHL (P=0.01). Results show that no significant difference was found in a -actinin-2 and a -actinins 3 expression levels between C and T animals in response to progressive RESISTANCE TRAINING (P=0.61 and P=0.19 respectively). Surprisingly, protein expression levels of a -actinin-2 decreased 12% and a -actinin-3 increased 13% following 8 week of RESISTANCE TRAINING between groups, but it wasn' t statistically significant. The results of this study demonstrate that progressive RESISTANCE TRAINING do not alters the expression level of a-actinins at the cellular levels in skeletal muscle and probably further investigations will indicate sarcomeric protein's response to exercise training.

Cites

References

Cite

APA: Copy

GAEINI, A.A., KHALEDI, N., RAVASI, A.A., SAHEBGHADAM LOTFI, A., HEDAYATI, M., ARABKARI, V., & SADR ALASHRAFI, S.. (2012). THE RESPONSE OF SKELETAL MUSCLE SARCOMERIC PROTEINS TO 8 WEEK PROGRESSIVE RESISTANCE T RAINING IN SPRAGUE-DAWLEY RATS. OLYMPIC, 19(4 (SERIAL 56)), 125-137. SID. https://sid.ir/paper/37833/en

Vancouver: Copy

GAEINI A.A., KHALEDI N., RAVASI A.A., SAHEBGHADAM LOTFI A., HEDAYATI M., ARABKARI V., SADR ALASHRAFI S.. THE RESPONSE OF SKELETAL MUSCLE SARCOMERIC PROTEINS TO 8 WEEK PROGRESSIVE RESISTANCE T RAINING IN SPRAGUE-DAWLEY RATS. OLYMPIC[Internet]. 2012;19(4 (SERIAL 56)):125-137. Available from: https://sid.ir/paper/37833/en

IEEE: Copy

A.A. GAEINI, N. KHALEDI, A.A. RAVASI, A. SAHEBGHADAM LOTFI, M. HEDAYATI, V. ARABKARI, and S. SADR ALASHRAFI, “THE RESPONSE OF SKELETAL MUSCLE SARCOMERIC PROTEINS TO 8 WEEK PROGRESSIVE RESISTANCE T RAINING IN SPRAGUE-DAWLEY RATS,” OLYMPIC, vol. 19, no. 4 (SERIAL 56), pp. 125–137, 2012, [Online]. Available: https://sid.ir/paper/37833/en

Related Journal Papers