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Information Journal Paper

Title

EFFECTS OF A MODERATELY-RESTRICTED CARBOHYDRATE DIET ON CARDIOVASCULAR RISK FACTORS AMONG WOMEN WITH METABOLIC SYNDROME

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Abstract

 Background: The growing epidemics of OBESITY and METABOLIC SYNDROME (MetS) have been accompanied with dietary fat restriction and carbohydrate elevation. We evaluated the efficacy of moderately-restricted carbohydrate diet on features of the MetS in women.Methods: In a randomized cross-over clinical trial, 30 overweight or obese (Body mass index>25 kg/m2) women with the MetS were enrolled. Subjects were randomly allocated to receive either a high-carbohydrate (HC) (60-65% carbohydrates, 20-25% fats) or a moderately-restricted carbohydrate (MRC) (43-47% carbohydrate, 36-40% fats) diet. Diets were continued for 6 weeks followed by a 2-week washout period. Anthropometrics, BLOOD PRESSURE and biochemical variables were measured before and after each intervention period.Findings: Despite similar weight loss in both diets, the efficacy of MRC diet in reducing waist (-3.9 vs. -2.6 cm; P=0.07) and hip circumferences (-2.7 vs. -1.5 cm; P=0.07) was marginally greater compared with HC diet. In contrast to HC diet, MRC diet resulted in favorable changes in serum triglyceride (TG) concentrations (0.13 vs. -31.3 mg/dL; P=0.07). This was also the case for TG to high density lipoprotein (HDL) -cholesterol ratio (-0.9 vs. -0.1; P=0.06). The reductions in systolic BLOOD PRESSURE (-8.93 vs. -2.97 mmHg; P=0.06) and diastolic BLOOD PRESSURE (-12.7 vs. -1.77 mmHg; P=0.001) by MRC diet were higher than those by HC diet. The prevalence of MetS was significantly decreased only by MRC diet (P=0.03).Conclusion: Partial replacement of dietary carbohydrates by unsaturated fats might be recommended as an effective strategy for treatment of MetS.

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    APA: Copy

    RAJAIE, SOMAYEH, AZADBAKHT, LEILA, KHAZAEI, MAJID, & ESMAILLZADEH, AHMAD. (2012). EFFECTS OF A MODERATELY-RESTRICTED CARBOHYDRATE DIET ON CARDIOVASCULAR RISK FACTORS AMONG WOMEN WITH METABOLIC SYNDROME. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 29(171), 0-0. SID. https://sid.ir/paper/380560/en

    Vancouver: Copy

    RAJAIE SOMAYEH, AZADBAKHT LEILA, KHAZAEI MAJID, ESMAILLZADEH AHMAD. EFFECTS OF A MODERATELY-RESTRICTED CARBOHYDRATE DIET ON CARDIOVASCULAR RISK FACTORS AMONG WOMEN WITH METABOLIC SYNDROME. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2012;29(171):0-0. Available from: https://sid.ir/paper/380560/en

    IEEE: Copy

    SOMAYEH RAJAIE, LEILA AZADBAKHT, MAJID KHAZAEI, and AHMAD ESMAILLZADEH, “EFFECTS OF A MODERATELY-RESTRICTED CARBOHYDRATE DIET ON CARDIOVASCULAR RISK FACTORS AMONG WOMEN WITH METABOLIC SYNDROME,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 29, no. 171, pp. 0–0, 2012, [Online]. Available: https://sid.ir/paper/380560/en

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