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Information Journal Paper

Title

Evaluation of the serum level of magnesium, manganese and selenium in patients with hypothyroidism, hyperthyroidism and thyroid cancer in Birjand city in 2018

Pages

  90-99

Abstract

 Background and Aim: Metabolic thyroid diseases is one of the most common diseases in adults. On the other hand, environmental pollutants, including heavy metals, can interfere with the functioning of hormones, hence, this study aimed to evaluate of the serum level of Magnesium, Manganese and Selenium in patients with hypothyroidism, hyperthyroidism and thyroid cancer in Birjand city in 2018. Materials and Methods: This was a descriptive-cross sectional study. 77 patients studied in three groups of hypothyroidism (n = 33), hyperthyroidism (n = 33) and thyroid cancer (n = 11) referred to endocrine clinic of Vale-Asr Hospital. In serum samples obtained from fasting venous samples, the concentration of metals was measured by ICP-MS and thyroid hormone levels were measured by ELISA kit. Data were analyzed using statistical tests of Kolmogorov-Smirnov, one-way ANOVA, Kruskal-Wallis, chisquare and Pearson’ s correlation coefficients by using R3. 3. 1 software. Results: Results showed that only the Manganese level was significantly different in the three groups (P <0. 05). The average level of Magnesium, Manganese, and Selenium in the hypothyroidism were 88. 7± 0. 5, 6. 30± 4. 8, and 1. 38± 0. 80; in the hyperthyroidism were 55. 7± 0. 4, 5. 5± 4. 1, and 1. 47± 0. 70; and in the thyroid cancer group were 2. 07± 0. 81, 6. 02± 2. 2 and 1. 8± 1. 3 μ g/l respectively. The results also showed the location of habitat in different groups had a statistically significant difference (P <0. 05). Conclusion: According to the findings of this study, although there is little relationship between the types of thyroid disorders and the serum levels of heavy metals, it is significant in the case of Manganese, which reveals the importance of further investigation.

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    APA: Copy

    MANSOURI, BORHAN, REZAEI, MARYAM, JAVADMOOSAVI, SEYED YOOSEF, & Amirabadi, Alireza. (2020). Evaluation of the serum level of magnesium, manganese and selenium in patients with hypothyroidism, hyperthyroidism and thyroid cancer in Birjand city in 2018. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 27(1 ), 90-99. SID. https://sid.ir/paper/381688/en

    Vancouver: Copy

    MANSOURI BORHAN, REZAEI MARYAM, JAVADMOOSAVI SEYED YOOSEF, Amirabadi Alireza. Evaluation of the serum level of magnesium, manganese and selenium in patients with hypothyroidism, hyperthyroidism and thyroid cancer in Birjand city in 2018. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;27(1 ):90-99. Available from: https://sid.ir/paper/381688/en

    IEEE: Copy

    BORHAN MANSOURI, MARYAM REZAEI, SEYED YOOSEF JAVADMOOSAVI, and Alireza Amirabadi, “Evaluation of the serum level of magnesium, manganese and selenium in patients with hypothyroidism, hyperthyroidism and thyroid cancer in Birjand city in 2018,” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 1 , pp. 90–99, 2020, [Online]. Available: https://sid.ir/paper/381688/en

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