AMNIOTIC FLUID OD 650 LEVEL AND ITS SENSITIVITY AND SPECIFICITY IN PREDICTION OF FETAL LUNG MATURITY

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KHEZERDOUST S.; BAHADORI F.; SHAFAAT M.; YAHYAZADEH H.; YAHYAZADEH N.; AMINI E.

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Journal: Tehran University Medical Journal Year:2009 | Volume:66 | Issue:10 Page(s): 704-707

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Title

AMNIOTIC FLUID OD 650 LEVEL AND ITS SENSITIVITY AND SPECIFICITY IN PREDICTION OF FETAL LUNG MATURITY

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Keywords

RESPIRATORY DISTRESS SYNDROME (RDS)Q3

FETALQ3

LUNGQ3

MATURITYQ3

TESTSQ3

OPTICALQ3

DENSITYQ3

PRETERM LABORQ3

Abstract

Background: Respiratory distress syndrome remains a common cause of neonatal morbidity and mortality. Consequently FETAL LUNG MATURITY (FLM) testing plays an important role in establishing obstetrics management strategies.Methods: This prospective study was performed on 80 pregnant women (between 28 to 40 weeks of gestation) and their neonates. Respiratory Distress Syndrome (RDS) had been diagnosed with presence of physical sign (grunting, retraction of intercostals muscles and thacypnea) and O2 requirement over the 24 hours and X -ray signs. The respiratory status of each newborn was evaluated standard clinical and radiographic criteria were used to diagnose RDS. The ability of amniotic fluid OPTICAL DENSITY (OD 650) was evaluated by calculating the sensitivity and specificity of each value. Results: Twenty (25%) infants developed RDS. OD 650nm more than 28% ratio predicted pulmonary MATURITY. Nineteen out of 20 RDS cases had been predicted correctly. The mean of weight of this neonates was 2043±511.68 and mean of gestational age was 32.3±20.43 weeks and mean of OD 650 was 0.134. The negative predictive value of OD 650nm> 0.28 ratio was 97% and positive predictive value was 51% and the sensitivity for prediction of RDS was 95% and specificity was 70%. Conclusions: measuring OPTICAL absorbance of amniotic fluid (OD 650) is a rapid simple and inexpensive procedure that compares favorably with other methods of FETAL MATURITY assessment.

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APA: Copy

KHEZERDOUST, S., BAHADORI, F., SHAFAAT, M., YAHYAZADEH, H., YAHYAZADEH, N., & AMINI, E.. (2009). AMNIOTIC FLUID OD 650 LEVEL AND ITS SENSITIVITY AND SPECIFICITY IN PREDICTION OF FETAL LUNG MATURITY. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 66(10), 704-707. SID. https://sid.ir/paper/38235/en

Vancouver: Copy

KHEZERDOUST S., BAHADORI F., SHAFAAT M., YAHYAZADEH H., YAHYAZADEH N., AMINI E.. AMNIOTIC FLUID OD 650 LEVEL AND ITS SENSITIVITY AND SPECIFICITY IN PREDICTION OF FETAL LUNG MATURITY. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2009;66(10):704-707. Available from: https://sid.ir/paper/38235/en

IEEE: Copy

S. KHEZERDOUST, F. BAHADORI, M. SHAFAAT, H. YAHYAZADEH, N. YAHYAZADEH, and E. AMINI, “AMNIOTIC FLUID OD 650 LEVEL AND ITS SENSITIVITY AND SPECIFICITY IN PREDICTION OF FETAL LUNG MATURITY,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 66, no. 10, pp. 704–707, 2009, [Online]. Available: https://sid.ir/paper/38235/en

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