ONE DECADE EXPERIENCE OF HEART TRANSPLANTATION IN IRAN

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MANDEGAR M.H.; SALEHI OMRAN A.; KAZAZ M.; MARASHI M.; JEBELI M.; GHANBARIAN Z.; FIROZI R.; EGHTESADI ARAGHI P.

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Journal: Annals of Military and Health Sciences Research Year:2003 | Volume:1 | Issue:2 (Serial Number 2) Page(s): 85-92

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Title

ONE DECADE EXPERIENCE OF HEART TRANSPLANTATION IN IRAN

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Keywords

POSTOPERATIVE COMPLICATIONSQ2

PRIMARY CARE PHYSICIANSQ3

REJECTIONQ4

SURVIVAL RATEQ4

Abstract

Background: Over the past decade, cardiac transplantation has evolved into an acceptable therapy for patients with end stage heart failure not amenable to conventional therapy. The purpose of this study was to determination of prognosis in Iranian patients receiving heart transplantation and assessing the improvement alternatives.Materials and Methods: This retrospective study reviews 32 patients who underwent orthotopic (30 patients) or heterotopic (2 patients) heart transplantation over a period of 10 years (between January 1992 and since December 2002) in Or. Shariati Hospital (Tehran Univ. of Medical Sciences). Indications of heart transplantation, outcome and mortality rate and their causes, one, three and five-year survival in cardiac transplant recipients were assessed.Results: The mean age was 32±11 years (range 12 to 45 years). There were 22 male and 11 female. 71.8 percent of patients have a NYHA class lll cardiac status and 28.2 percent with a NYHA class IV. The indications for transplantation included: dilated cardiomyopathy in 81 percent, and ischemic cardiomyopathy in 19 percent. The median follow-up period was 24 months (ranging 2 to 110). 19 patients (59.4 percent) have 36 serious POSTOPERATIVE COMPLICATIONS (including acute REJECTION, infection, hepatic and renal failure, heart failure and pericardial effusion). Of the 32 patients who had heart transplants, 15 patients (47 percent) died during the study period, 1 day to 2 year after transplantation. Overall survival at one year, three year and five year was 39.1 percent (95% Cl, 17.5 percent to 60.7 percent), was 34.8 percent (95% Cl, 13.7 percent to 55.8 percent) and 30.4 percent (95% Cl, 10.1 percent to 50.8 percent) respectively. Main causes of death were respectively including REJECTION, infection and sepsis and heart failure.Conclusion: Finally the authors recommended that however there are numerous factors affecting SURVIVAL RATEs, and there is a long way to come aggress developed countries results, in future studies the role of follow up system and postoperative cares and the position of the PRIMARY CARE PHYSICIANS in improving the SURVIVAL RATEs, could be assessed.

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APA: Copy

MANDEGAR, M.H., SALEHI OMRAN, A., KAZAZ, M., MARASHI, M., JEBELI, M., GHANBARIAN, Z., FIROZI, R., & EGHTESADI ARAGHI, P.. (2003). ONE DECADE EXPERIENCE OF HEART TRANSPLANTATION IN IRAN. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, 1(2 (Serial Number 2)), 85-92. SID. https://sid.ir/paper/382632/en

Vancouver: Copy

MANDEGAR M.H., SALEHI OMRAN A., KAZAZ M., MARASHI M., JEBELI M., GHANBARIAN Z., FIROZI R., EGHTESADI ARAGHI P.. ONE DECADE EXPERIENCE OF HEART TRANSPLANTATION IN IRAN. ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH[Internet]. 2003;1(2 (Serial Number 2)):85-92. Available from: https://sid.ir/paper/382632/en

IEEE: Copy

M.H. MANDEGAR, A. SALEHI OMRAN, M. KAZAZ, M. MARASHI, M. JEBELI, Z. GHANBARIAN, R. FIROZI, and P. EGHTESADI ARAGHI, “ONE DECADE EXPERIENCE OF HEART TRANSPLANTATION IN IRAN,” ANNALS OF MILITARY AND HEALTH SCIENCES RESEARCH, vol. 1, no. 2 (Serial Number 2), pp. 85–92, 2003, [Online]. Available: https://sid.ir/paper/382632/en

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