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Information Journal Paper

Title

DIAGNOSIS OF FUNGAL KERATITIS IN PATIENTS WITH CORNEAL LESIONS AT AMIRALMOMENIN HOSPITAL IN RASHT, IRAN

Pages

  374-380

Abstract

 Background: Keratomycosis is a fungal infection of the cornea which could be sightthreatening and even causes eye loss. Considering the high humidity and the dominance of agriculture as important predisposing factors of keratomycosis in north of IRAN, this study was carried out for diagnosis of fungal KERATITIS in patients with corneal lesions in Rasht, Gilan province, IRAN.Methods: This descriptive cross-sectional study was conducted from July 2015 to November 2016 on 56 patients with corneal lesion suspected to keratomycosis and referred to eye emergency ward of Amiralmomenin hospital, Rasht, IRAN. Corneal scraping was performed in all cases and specimens were subjected to direct examination and culture. Only colonies grown in sites of corneal scraping inoculation were considered significant. Fungal isolates were identified according to their macroscopic features of colonies and microscopic characteristics in slide cultures. Data were analyzed in SPSS software, version 21 (IBM SPSS, Armonk, NY, USA) and P<0.05 was considered significant.Results: The patients included 42 (75%) men and 14 (25%) women with the mean age of 49.5 years (9 to 90 years). Positive culture was observed in 9 cases but, only in one of these patients direct examination was positive and fungal elements were seen in 10% KOH preparation. Though, fungal KERATITIS was confirmed in 9 (16%) patients including seven (77.8%) men and two (22.2%) women. The majority of cases (88.9%) had a history of corneal trauma with plants and they were mainly farmer. According to statistical analysis, there was a significant association between corneal trauma and keratomycosis (P=0.007). The most common etiologic agents wereFusarium spp. (n: 4, 44.4%), followed byAspergillus flavus (n: 2, 22.2%), Penicillium sp. (n: 1, 11.1%), Acremoniumsp. (n: 1, 11.1%), and Cladosporium sp. (n: 1, 11.1%) respectively.Conclusion: In the presence of sufficient predisposing factors such as corneal injuries caused by plants, keratomycosis could be caused by a variety of fungi. Furthermore, low sensitivity of direct examination in this study, revealed the necessity of culture in diagnosis of keratomycosis.

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    APA: Copy

    TIGHNAVARD BEJARBANE, RHOGHAYE, DAIE GHAZVINI, ROSHANAK, MAHMOUDI, SHAHRAM, SOLTANI MOGHADAM, REZA, SAFARA, MAHIN, Bakhshi, Heidar, & KORDBACHEH, PARIVASH. (2017). DIAGNOSIS OF FUNGAL KERATITIS IN PATIENTS WITH CORNEAL LESIONS AT AMIRALMOMENIN HOSPITAL IN RASHT, IRAN. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 75(5), 374-380. SID. https://sid.ir/paper/38270/en

    Vancouver: Copy

    TIGHNAVARD BEJARBANE RHOGHAYE, DAIE GHAZVINI ROSHANAK, MAHMOUDI SHAHRAM, SOLTANI MOGHADAM REZA, SAFARA MAHIN, Bakhshi Heidar, KORDBACHEH PARIVASH. DIAGNOSIS OF FUNGAL KERATITIS IN PATIENTS WITH CORNEAL LESIONS AT AMIRALMOMENIN HOSPITAL IN RASHT, IRAN. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2017;75(5):374-380. Available from: https://sid.ir/paper/38270/en

    IEEE: Copy

    RHOGHAYE TIGHNAVARD BEJARBANE, ROSHANAK DAIE GHAZVINI, SHAHRAM MAHMOUDI, REZA SOLTANI MOGHADAM, MAHIN SAFARA, Heidar Bakhshi, and PARIVASH KORDBACHEH, “DIAGNOSIS OF FUNGAL KERATITIS IN PATIENTS WITH CORNEAL LESIONS AT AMIRALMOMENIN HOSPITAL IN RASHT, IRAN,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 75, no. 5, pp. 374–380, 2017, [Online]. Available: https://sid.ir/paper/38270/en

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